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Query: UBE2S

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UBE2S 0 -4.439 0.660 -0.630 -0.879 -0.110

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UBE2S Ubiquitylation K198 -1.509 -1.940 _ALASGTEASSTDPGAPGGPGGAEGPMAKK(gl)_

Background Information for UBE2S:


Pubmed-UBE2S »
Uniprot-UBE2S »
Biogrid-UBE2S »
ProteomicsDB-UBE2S »

Tumorportal-UBE2S »
COSMIC-UBE2S »
GenomeRNAi-UBE2S »
Genecards-UBE2S


Protein-protein Interactions for UBE2S
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait UBE2S Cat. description Hein, Mann, Cell 2015
Category members IP bait C11orf74 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC4C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YAF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in UBE2S
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UBQ-conjugat_E2 IPR000608 0
Category members UBQ-conjugating_enzyme/RWD IPR016135 0


Protein complexes (CORUM database) featuring UBE2S
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring UBE2S
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process Database 2.59
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members Pathway Pathway_888 KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 0 2.22
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members GO Category GO:0005680 anaphase-promoting complex Database 0.63
Category members GO Category GO:0070979 protein K11-linked ubiquitination Database 0.25
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0010458 exit from mitosis Database 0.2
Category members GO Category GO:0044314 protein K27-linked ubiquitination Database 0.13
Category members GO Category GO:0010994 free ubiquitin chain polymerization Database 0.08
Category members GO Category GO:0006464 cellular protein modification process Database 0
Category members GO Category GO:0016881 acid-amino acid ligase activity Database 0
Category members GO Category GO:0035519 protein K29-linked ubiquitination Database 0
Category members GO Category GO:0051488 activation of anaphase-promoting complex activity Database 0
Category members GO Category GO:0070534 protein K63-linked ubiquitination Database 0


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