Results for the Category
activation of anaphase-promoting complex activity
(GO:0051488)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| FZR1 | 0 | 0.740 | -0.470 | |||||
| UBE2S | 0 | 0.660 | -0.630 | -0.879 | -0.110 | |||
| CDC20 | 0 | 0.030 | 0.220 | -0.353 | -1.700 | |||
| UBE2C | 0 | -0.130 | -0.650 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| CDC20 | Phosphorylation | S41 | -2.364 | _EAAGPAPS(ph)PMR_ | |
| CDC20 | Phosphorylation | T70 | -0.739 | -0.822 | _VQTT(ph)PSKPGGDR_ |
| CDC20 | Ubiquitylation | K136 | -1.643 | -0.774 | _LSGK(gl)PQNAPEGYQNR_ |
| CDC20 | Ubiquitylation | K149 | -1.522 | -0.046 | _LK(gl)VLYSQK_ |
| CDC20 | Ubiquitylation | K155 | -1.662 | -1.144 | _VLYSQK(gl)ATPGSSR_ |
| CDC20 | Ubiquitylation | K490 | -0.793 | -0.202 | _ASAAK(gl)SSLIHQGIR_ |
| FZR1 | Ubiquitylation | K135 | -0.177 | _GLFTYSLSTK(gl)R_ | |
| FZR1 | Ubiquitylation | K263 | 0.187 | _GFVQIWDAAAGKK(gl)_ | |
| UBE2C | Phosphorylation | S3 | -0.676 | 1.443 | _(ac)AS(ph)QNRDPAATSVAAAR_ |
| UBE2C | Phosphorylation | T11 | 1.337 | _(ac)ASQNRDPAAT(ph)SVAAAR_ | |
| UBE2C | Ubiquitylation | K121 | -0.180 | _EK(gl)WSALYDVR_ | |
| UBE2S | Ubiquitylation | K198 | -1.509 | -1.940 | _ALASGTEASSTDPGAPGGPGGAEGPMAKK(gl)_ |
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