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Query: TRRAP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TRRAP 1 3.599 0.160 -0.850 0.247 0.326 -1.904
TRRAP 1 3.599 0.160 -0.850 -0.022 -0.416 0.113

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TRRAP Phosphorylation S2077 2.328 1.169 _SQS(ph)LPGADSLLAK_
TRRAP Phosphorylation S2075 1.092 _S(ph)QSLPGADSLLAKPIDK_
TRRAP Phosphorylation S2051 2.162 1.088 _GLS(ph)VDSAQEVK_
TRRAP Ubiquitylation K2207 0.024 _GIAACMTCGNTK(gl)VLR_
TRRAP Ubiquitylation K551 -0.015 _SLVK(gl)TLVCGVK_
TRRAP Ubiquitylation K2972 -1.153 -0.677 _TVVK(gl)TWR_
TRRAP Ubiquitylation K2059 -0.686 _GLSVDSAQEVK(gl)R_
TRRAP Ubiquitylation K1749 -0.941 _NYSIAQK(gl)R_
TRRAP Ubiquitylation K3508 -0.636 -1.402 _VEIVQK(gl)HNTAAR_
TRRAP Ubiquitylation K3598 -0.170 -1.798 _LVEDNPSSLSLVEIYK(gl)QR_
TRRAP Ubiquitylation K2968 -0.907 -2.144 _NNSLHDM(ox)K(gl)TVVK_

Background Information for TRRAP:


Pubmed-TRRAP »
Uniprot-TRRAP »
Biogrid-TRRAP »
ProteomicsDB-TRRAP »

Tumorportal-TRRAP »
COSMIC-TRRAP »
GenomeRNAi-TRRAP »
Genecards-TRRAP


Protein-protein Interactions for TRRAP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC101 Cat. description Hein, Mann, Cell 2015
Category members IP bait ING3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MPHOSPH8 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH10 Cat. description Hein, Mann, Cell 2015
Category members IP bait NCBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NCK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TRRAP Cat. description Hein, Mann, Cell 2015
Category members IP bait YEATS4 Cat. description Hein, Mann, Cell 2015
Category members IP bait ATXN7L3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C20orf20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CACNG5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CREB3L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H2BA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KAT5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MEAF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MORF4L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MORF4L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYCL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RUVBL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RUVBL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCN3B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STAT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TADA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TADA2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TADA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TAF6L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YEATS4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TRRAP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members PI3/4_kinase_cat_dom IPR000403 1.52
Category members FATC IPR003152 0.68
Category members PIK_FAT IPR014009 0.68
Category members PIK-rel_kinase_FAT IPR003151 0.16
Category members Kinase-like_dom IPR011009 0.03


Protein complexes (CORUM database) featuring TRRAP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 627 MRN-TRRAP complex (MRE11A-RAD50-NBN-TRRAP complex) Database 1.09
Category members Corum 1166 p400-associated complex Database 0.68
Category members Corum 525 TIP60 histone acetylase complex Database 0.62
Category members Corum 475 STAGA complex (SPT3-TAF9-GCN5 acetyltransferase complex) Database 0.33
Category members Corum 2857 NuA4/Tip60 HAT complex Database 0.28
Category members Corum 798 NuA4/Tip60-HAT complex A Database 0.28
Category members Corum 787 NuA4/Tip60-HAT complex B Database 0.23
Category members Corum 476 STAGA complex (SPT3-TAF9-GCN5 acetyltransferase complex) Database 0.2
Category members Corum 441 TFTC-type histone acetyl transferase complex Database 0.2
Category members Corum 1170 cMYC-ATPase-helicase complex Database 0.16
Category members Corum 1171 c-MYC-ATPase-helicase complex Database 0.16
Category members Corum 2856 NuA4/Tip60 HAT complex Database 0.13
Category members Corum 471 PCAF complex Database 0.08
Category members Corum 477 PCAF complex Database 0.08
Category members Corum 528 NuA4/Tip60 HAT complex Database 0.07
Category members Corum 445 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.05
Category members Corum 455 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.05
Category members Corum 456 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.05
Category members Corum 459 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.05
Category members Corum 462 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.05
Category members Corum 513 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.05
Category members Corum 438 GCN5-TRRAP histone acetyltransferase complex Database 0.05
Category members Corum 799 DMAP1-associated complex Database 0.05
Category members Corum 529 NuA4/Tip60 HAT complex Database 0.04
Category members Corum 470 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.02
Category members Corum 1175 TRRAP-BAF53-HAT complex Database 0


Categories featuring TRRAP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0016573 histone acetylation Database 1.24
Category members Pathway Pathway_65 PID_MYC_ACTIV_PATHWAY 0 1.08
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_325 PID_E2F_PATHWAY 0 0.62
Category members Pathway Pathway_199 PID_BETA_CATENIN_NUC_PATHWAY 0 0.53
Category members Pathway Pathway_1176 BIOCARTA_PITX2_PATHWAY 0 0.29
Category members GO Category GO:0007093 mitotic cell cycle checkpoint Database 0.27
Category members Pathway Pathway_383 PID_P53_DOWNSTREAM_PATHWAY 0 0.23
Category members GO Category GO:0003712 transcription cofactor activity Database 0.21
Category members GO Category GO:0030914 STAGA complex Database 0.2
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members Pathway Pathway_858 PID_MYC_PATHWAY 0 0.17
Category members GO Category GO:0035267 NuA4 histone acetyltransferase complex Database 0.07
Category members GO Category GO:0033276 transcription factor TFTC complex Database 0.06
Category members GO Category GO:0043968 histone H2A acetylation Database 0.02
Category members GO Category GO:0000125 PCAF complex Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0016578 histone deubiquitination Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0016773 phosphotransferase activity, alcohol group as acceptor Database 0
Category members GO Category GO:0043967 histone H4 acetylation Database 0


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