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Query: TRA2B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TRA2B 0 2.906 0.620 -0.400 0.394 0.079 0.463 0.352 0.209

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TRA2B Phosphorylation S2 0.810 1.077 _(ac)S(ph)DSGEQNYGER_
TRA2B Phosphorylation S14 0.874 0.868 _(ac)SDS(ph)GEQNYGERES(ph)R_
TRA2B Phosphorylation S4 0.502 0.615 _(ac)SDS(ph)GEQNYGERES(ph)R_
TRA2B Phosphorylation T201 -0.428 -0.429 _RPHT(ph)PTPGIYMGR_

Background Information for TRA2B:





Protein-protein Interactions for TRA2B

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DDB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C11orf57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELAVL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRA2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait U2AF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TRA2B

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34


Protein complexes (CORUM database) featuring TRA2B

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 1261 SRm160/300 complex Database 0.02


Categories featuring TRA2B

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0003729 mRNA binding Database 1.38
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0000375 RNA splicing, via transesterification reactions Database 0.73
Category members GO Category GO:0000381 regulation of alternative mRNA splicing, via spliceosome Database 0.5
Category members GO Category GO:0000302 response to reactive oxygen species Database 0.35
Category members GO Category GO:0048026 positive regulation of mRNA splicing, via spliceosome Database 0.04


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