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Query: TMX1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TMX1 0 1.622 -0.010 0.926 -1.118 0.145 0.027

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TMX1 Phosphorylation S270 0.589 0.579 _S(ph)LGPSLATDKS_
TMX1 Phosphorylation S274 0.561 _SLGPS(ph)LATDKS_
TMX1 Ubiquitylation K279 -0.052 0.536 _SLGPSLATDK(gl)S_
TMX1 Phosphorylation S247 0.548 0.425 _VEEEQEADEEDVS(ph)EEEAESK_
TMX1 Ubiquitylation K233 -0.752 0.034 _LLSESAQPLK(gl)K_
TMX1 Ubiquitylation K234 0.013 _LLSESAQPLK(gl)K_
TMX1 Ubiquitylation K223 -0.915 _K(gl)LLSESAQPLKK_

Background Information for TMX1:


Pubmed-TMX1 »
Uniprot-TMX1 »
Biogrid-TMX1 »
ProteomicsDB-TMX1 »

Tumorportal-TMX1 »
COSMIC-TMX1 »
GenomeRNAi-TMX1 »
Genecards-TMX1


Protein-protein Interactions for TMX1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait COLEC12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IGSF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL27RA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZPLD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TMX1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Thioredoxin_domain IPR013766 0.49
Category members Thioredoxin-like_fold IPR012336 0.16


Protein complexes (CORUM database) featuring TMX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TMX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0006260 DNA replication Database 3.34
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0006888 ER to Golgi vesicle-mediated transport Database 0.28
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0045454 cell redox homeostasis Database 0.05
Category members GO Category GO:0015036 disulfide oxidoreductase activity Database 0.05
Category members GO Category GO:0006950 response to stress Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0045321 leukocyte activation Database 0
Category members GO Category GO:0045927 positive regulation of growth Database 0


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