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Query: TMEM109

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TMEM109 0 -3.480 1.100 -0.740 -0.686 0.258 -1.625 -0.139 -0.225

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TMEM109 Ubiquitylation K215 0.498 _ASGAQLEAK(gl)VR_
TMEM109 Ubiquitylation K46 -1.303 -0.093 _RDFAPPGQQK(gl)R_

Background Information for TMEM109:


Pubmed-TMEM109 »
Uniprot-TMEM109 »
Biogrid-TMEM109 »
ProteomicsDB-TMEM109 »

Tumorportal-TMEM109 »
COSMIC-TMEM109 »
GenomeRNAi-TMEM109 »
Genecards-TMEM109


Protein-protein Interactions for TMEM109
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATL3 Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait MMGT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2CA Cat. description Hein, Mann, Cell 2015
Category members IP bait PSMB4 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB2A Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait RASSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM109 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM63B Cat. description Hein, Mann, Cell 2015


Protein Domains in TMEM109
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring TMEM109
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TMEM109
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0031965 nuclear membrane Database 2.59
Category members GO Category GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Database 0.83
Category members GO Category GO:0005640 nuclear outer membrane Database 0.18
Category members GO Category GO:0003674 molecular_function Database 0.08
Category members GO Category GO:0033017 sarcoplasmic reticulum membrane Database 0
Category members GO Category GO:0060548 negative regulation of cell death Database 0


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