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Query: TIAL1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TIAL1 0 0.559 -0.540 0.100
TIAL1 0 0.559 -0.540 0.100 -0.721 -0.259 -0.319 -0.332 -0.199

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TIAL1 Ubiquitylation K122 0.503 0.809 _SAFAPFGK(gl)ISDAR_
TIAL1 Ubiquitylation K91 0.902 _VNWATTPSSQKK(gl)_

Background Information for TIAL1:


Pubmed-TIAL1 »
Uniprot-TIAL1 »
Biogrid-TIAL1 »
ProteomicsDB-TIAL1 »

Tumorportal-TIAL1 »
COSMIC-TIAL1 »
GenomeRNAi-TIAL1 »
Genecards-TIAL1


Protein-protein Interactions for TIAL1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KBTBD7 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF2A Cat. description Hein, Mann, Cell 2015
Category members IP bait MAPK3 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP6R1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DZIP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SAV1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TIAL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TIAL1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members RRM_dom_euk IPR003954 0.18


Protein complexes (CORUM database) featuring TIAL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TIAL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0010494 cytoplasmic stress granule Database 1.32
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0006952 defense response Database 0.32
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0005764 lysosome Database 0
Category members GO Category GO:0007281 germ cell development Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0017091 AU-rich element binding Database 0
Category members GO Category GO:0017145 stem cell division Database 0


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