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Query: THOC6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
THOC6 0 -0.319 0.100 -0.300 -0.547 0.540 0.379 -0.405 -0.286

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for THOC6:


Pubmed-THOC6 »
Uniprot-THOC6 »
Biogrid-THOC6 »
ProteomicsDB-THOC6 »

Tumorportal-THOC6 »
COSMIC-THOC6 »
GenomeRNAi-THOC6 »
Genecards-THOC6


Protein-protein Interactions for THOC6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ABI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait BCLAF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C17orf85 Cat. description Hein, Mann, Cell 2015
Category members IP bait ID1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait THOC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait THOC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait THOC5 Cat. description Hein, Mann, Cell 2015
Category members IP bait THOC7 Cat. description Hein, Mann, Cell 2015
Category members IP bait THOC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THOC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in THOC6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52


Protein complexes (CORUM database) featuring THOC6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 770 TREX complex Database 1.46
Category members Corum 774 THO complex Database 0.35


Categories featuring THOC6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0006406 mRNA export from nucleus Database 4.09
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0046784 viral mRNA export from host cell nucleus Database 1.46
Category members GO Category GO:0000346 transcription export complex Database 1.18
Category members GO Category GO:0000445 THO complex part of transcription export complex Database 0.67
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0000347 THO complex Database 0.35
Category members GO Category GO:0007417 central nervous system development Database 0


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