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Query: TFAM

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TFAM 0 2.251 1.980 -1.290 0.204 0.244 0.179 0.349

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TFAM Phosphorylation S193 1.208 1.236 _NLS(ph)DSEKELYIQHAK_
TFAM Phosphorylation S195 0.801 1.180 _NLSDS(ph)EKELYIQHAK_
TFAM Ubiquitylation K76 -1.169 _AQNPDAK(gl)TTELIR_

Background Information for TFAM:


Pubmed-TFAM »
Uniprot-TFAM »
Biogrid-TFAM »
ProteomicsDB-TFAM »

Tumorportal-TFAM »
COSMIC-TFAM »
GenomeRNAi-TFAM »
Genecards-TFAM


Protein-protein Interactions for TFAM
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GOPC Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TFAM
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members HMG_box_dom IPR009071 0.31


Protein complexes (CORUM database) featuring TFAM
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TFAM
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_350 REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION 0 7.97
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0031072 heat shock protein binding Database 1.59
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006356 regulation of transcription from RNA polymerase I promoter Database 0.73
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0042645 mitochondrial nucleoid Database 0.61
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0006261 DNA-dependent DNA replication Database 0.48
Category members Pathway Pathway_32 KEGG_HUNTINGTONS_DISEASE 0 0.46
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0033108 mitochondrial respiratory chain complex assembly Database 0.18
Category members GO Category GO:0006390 transcription from mitochondrial promoter Database 0.07
Category members GO Category GO:0006391 transcription initiation from mitochondrial promoter Database 0
Category members GO Category GO:0008301 DNA binding, bending Database 0


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