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Query: TDP2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TDP2 0 -0.697 0.200 -0.360

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TDP2 Ubiquitylation K23 -0.309 -0.581 _EAAEEEGEPEVK(gl)K_
TDP2 Ubiquitylation K24 -0.914 -0.896 _EAAEEEGEPEVKK(gl)_
TDP2 Ubiquitylation K203 -0.460 -0.913 _SQEIIPFPSTK(gl)MMR_
TDP2 Ubiquitylation K192 -0.116 -1.471 _LK(gl)SQEIIPFPSTK_
TDP2 Ubiquitylation K82 -1.178 -1.657 _RPETISEPK(gl)TYVDLTNEETTDSTTSK_
TDP2 Ubiquitylation K341 -0.167 _SLDLLGLEK(gl)LDCGR_

Background Information for TDP2:


Pubmed-TDP2 »
Uniprot-TDP2 »
Biogrid-TDP2 »
ProteomicsDB-TDP2 »

Tumorportal-TDP2 »
COSMIC-TDP2 »
GenomeRNAi-TDP2 »
Genecards-TDP2


Protein-protein Interactions for TDP2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AZIN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GORASP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLA2G10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RSBN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCEAL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TDP2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UBA-like IPR009060 0.17
Category members Endo/exonuclease/phosphatase IPR005135 0


Protein complexes (CORUM database) featuring TDP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TDP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006302 double-strand break repair Database 4.62
Category members GO Category GO:0003697 single-stranded DNA binding Database 4.24
Category members GO Category GO:0016605 PML body Database 1.41
Category members GO Category GO:0007166 cell surface receptor signaling pathway Database 0.1
Category members GO Category GO:0004518 nuclease activity Database 0.09
Category members Pathway Pathway_986 PID_CD40_PATHWAY 0 0
Category members GO Category GO:0000287 magnesium ion binding Database 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0030145 manganese ion binding Database 0


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