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Query: TCOF1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TCOF1 3 9.828 -1.970 3.410 -0.231 -0.248
TCOF1 3 9.828 -1.970 3.410 0.562 0.635 0.077 0.240

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TCOF1 Phosphorylation S1447 2.418 2.296 _GSLGS(ph)QGAKDEPEEELQK_
TCOF1 Phosphorylation S1387 0.202 0.572 _RKLS(ph)GDQPAAR_
TCOF1 Phosphorylation S1265 0.630 0.536 _LDSS(ph)PSVSSTLAAK_
TCOF1 Phosphorylation S1264 0.678 0.451 _LDS(ph)SPSVSSTLAAK_
TCOF1 Phosphorylation S233 0.678 0.440 _ASSVSTKES(ph)PARK_
TCOF1 Phosphorylation S375 0.402 0.388 _TSQVGAAS(ph)APAKESPR_
TCOF1 Phosphorylation S1415 0.408 0.363 _KLGAGEGGEASVS(ph)PEK_
TCOF1 Phosphorylation S1294 -0.196 0.220 _QEAKPQQAAGMLS(ph)PK_
TCOF1 Phosphorylation S229 0.299 0.206 _ASSVS(ph)TKESPARK_
TCOF1 Phosphorylation S153 0.017 0.008 _TVANLLS(ph)GKSPRK_
TCOF1 Phosphorylation S1444 2.608 -0.001 _GKGS(ph)LGSQGAKDEPEEELQK_
TCOF1 Phosphorylation S381 0.138 -0.097 _AASAPAKES(ph)PRK_
TCOF1 Phosphorylation S1004 -0.550 -0.134 _S(ph)PAGPAATPAQAQAASTPR_
TCOF1 Phosphorylation S1148 -0.197 -0.145 _TQPSSGVDSAVGTLPATS(ph)PQSTSVQAK_
TCOF1 Phosphorylation T249 -0.318 -0.148 _VGDVT(ph)PQVK_
TCOF1 Phosphorylation S156 -0.143 -0.271 _TVANLLSGKS(ph)PR_
TCOF1 Phosphorylation T168 -0.150 -0.291 _SAEPSANTT(ph)LVSETEEEGSVPAFGAAAK_
TCOF1 Phosphorylation S1110 -0.328 -0.294 _KQEGPATQVDSAVGTLPATS(ph)PQSTSVQAK_
TCOF1 Phosphorylation S171 -0.009 -0.319 _SAEPSANTTLVS(ph)ETEEEGSVPAFGAAAK_
TCOF1 Phosphorylation S906 -0.124 -0.506 _AALAPAKES(ph)PRK_
TCOF1 Phosphorylation S583 -0.585 -0.527 _PTSS(ph)PAKGPPQK_
TCOF1 Phosphorylation T533 -0.351 -0.618 _VGPAT(ph)PSAQVGK_
TCOF1 Phosphorylation T914 -0.746 -0.672 _KGAAPT(ph)PPGK_
TCOF1 Phosphorylation S503 -0.705 -0.696 _S(ph)PQVKPASTMGMGPLGK_
TCOF1 Phosphorylation T173 -0.095 -0.774 _KSAEPSANTTLVSET(ph)EEEGSVPAFGAAAK_
TCOF1 Phosphorylation T581 -0.867 -1.151 _SLGNILQAKPT(ph)SSPAKGPPQK_
TCOF1 Phosphorylation S582 -0.697 -1.210 _SLGNILQAKPTS(ph)SPAKGPPQK_
TCOF1 Phosphorylation S1019 -1.826 -2.344 _SPAGPAATPAQAQAAS(ph)TPR_
TCOF1 Phosphorylation T1020 -1.928 -2.528 _SPAGPAATPAQAQAAST(ph)PR_
TCOF1 Phosphorylation S178 -0.673 _KSAEPSANTTLVSETEEEGS(ph)VPAFGAAAK_
TCOF1 Phosphorylation T230 0.667 _ASSVST(ph)KESPARK_
TCOF1 Phosphorylation S1413 0.285 _LGAGEGGEAS(ph)VSPEKTSTTSK_

Background Information for TCOF1:


Pubmed-TCOF1 »
Uniprot-TCOF1 »
Biogrid-TCOF1 »
ProteomicsDB-TCOF1 »

Tumorportal-TCOF1 »
COSMIC-TCOF1 »
GenomeRNAi-TCOF1 »
Genecards-TCOF1


Protein-protein Interactions for TCOF1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AKT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARRB2 Cat. description Hein, Mann, Cell 2015
Category members IP bait BAG6;BAT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait BECN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait L1TD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PAPSS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RASSF8 Cat. description Hein, Mann, Cell 2015
Category members IP bait SORT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARRB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAMKV Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DENND2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TCOF1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Treacle-like_TCS IPR017859 0.35
Category members LisH_dimerisation IPR006594 0.06


Protein complexes (CORUM database) featuring TCOF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3055 Nop56p-associated pre-rRNA complex Database INF


Categories featuring TCOF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Disease phenotype Treacher-Collins_syndrome Treacher-Collins syndrome Database 0.09
Category members GO Category GO:0001501 skeletal system development Database 0
Category members GO Category GO:0005215 transporter activity Database 0


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