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Query: TBC1D4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TBC1D4 0 0.168 1.700 -0.820 -0.137 -2.080

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TBC1D4 Phosphorylation S591 0.887 1.498 _LGSVDS(ph)FER_
TBC1D4 Phosphorylation S751 0.968 _TSS(ph)T(ph)CSNESLSVGGTSVTPR_
TBC1D4 Phosphorylation T752 0.968 _TSS(ph)T(ph)CSNESLSVGGTSVTPR_
TBC1D4 Phosphorylation S754 0.832 0.968 _TS(ph)STCS(ph)NESLSVGGTSVTPR_
TBC1D4 Phosphorylation S569 0.531 0.754 _SLTS(ph)SLENIFSR_
TBC1D4 Phosphorylation S588 0.602 0.593 _LGS(ph)VDSFER_
TBC1D4 Phosphorylation S570 0.511 0.509 _SLTSS(ph)LENIFSR_
TBC1D4 Phosphorylation S666 0.266 0.439 _AQGVRS(ph)PLLR_
TBC1D4 Phosphorylation S341 -0.345 -0.244 _HAS(ph)APSHVQPSDSEK_
TBC1D4 Phosphorylation S262 -2.075 _GPDPGEDLADLEVVVPGS(ph)PGDCLPEEADGTDTHLGLPAGASQPALTSSR_
TBC1D4 Phosphorylation S787 0.077 _VASPMNKS(ph)PSAMQQQDGLDR_

Background Information for TBC1D4:


Pubmed-TBC1D4 »
Uniprot-TBC1D4 »
Biogrid-TBC1D4 »
ProteomicsDB-TBC1D4 »

Tumorportal-TBC1D4 »
COSMIC-TBC1D4 »
GenomeRNAi-TBC1D4 »
Genecards-TBC1D4


Protein-protein Interactions for TBC1D4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CHAMP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MBOAT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MPHOSPH8 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait APBB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCNA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COMMD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CTDSP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF4E3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IQCF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC8E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TKT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMOD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMOD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TP53INP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TBC1D4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Rab-GTPase-TBC_dom IPR000195 0.05
Category members PTB/PI_dom IPR006020 0
Category members DUF3350 IPR021785 0


Protein complexes (CORUM database) featuring TBC1D4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TBC1D4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_934 PID_PI3KCI_AKT_PATHWAY 0 2.5
Category members Pathway Pathway_455 PID_INSULIN_GLUCOSE_PATHWAY 0 1.7
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0032869 cellular response to insulin stimulus Database 0.63
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members GO Category GO:0005097 Rab GTPase activator activity Database 0.3
Category members GO Category GO:0032313 regulation of Rab GTPase activity Database 0.04
Category members GO Category GO:0031339 negative regulation of vesicle fusion Database 0
Category members GO Category GO:0031988 membrane-bounded vesicle Database 0


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