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Query: TAF6L

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TAF6L 0 -2.150 0.320 -0.810
TAF6L 0 -2.150 0.320 -0.810 0.378 -1.536

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TAF6L Ubiquitylation K549 -0.992 _DVFQK(gl)SR_

Background Information for TAF6L:


Pubmed-TAF6L »
Uniprot-TAF6L »
Biogrid-TAF6L »
ProteomicsDB-TAF6L »

Tumorportal-TAF6L »
COSMIC-TAF6L »
GenomeRNAi-TAF6L »
Genecards-TAF6L


Protein-protein Interactions for TAF6L
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC101 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC101 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPINT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TADA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TADA2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TADA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TAF5L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TAF6L Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TAF6L
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DUF1546 IPR011442 0.33
Category members TAF_TATA-bd IPR004823 0.32
Category members Histone-fold IPR009072 0.01


Protein complexes (CORUM database) featuring TAF6L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 475 STAGA complex (SPT3-TAF9-GCN5 acetyltransferase complex) Database 0.33
Category members Corum 476 STAGA complex (SPT3-TAF9-GCN5 acetyltransferase complex) Database 0.2
Category members Corum 471 PCAF complex Database 0.08
Category members Corum 477 PCAF complex Database 0.08
Category members Corum 445 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.05
Category members Corum 455 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.05
Category members Corum 456 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.05
Category members Corum 459 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.05
Category members Corum 462 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.05
Category members Corum 513 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.05
Category members Corum 470 TFTC complex (TATA-binding protein-free TAF-II-containing complex) Database 0.02


Categories featuring TAF6L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006338 chromatin remodeling Database 4.95
Category members GO Category GO:0006352 DNA-dependent transcription, initiation Database 3.76
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0004402 histone acetyltransferase activity Database 0.56
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0030914 STAGA complex Database 0.2
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0051090 regulation of sequence-specific DNA binding transcription factor activity Database 0.02
Category members Pathway Pathway_856 KEGG_BASAL_TRANSCRIPTION_FACTORS 0 0
Category members GO Category GO:0000118 histone deacetylase complex Database 0
Category members GO Category GO:0043966 histone H3 acetylation Database 0


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