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Query: SYNCRIP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SYNCRIP 0 5.235 -1.170 2.050
SYNCRIP 0 5.235 -1.170 2.050 0.328 -0.116 0.051

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SYNCRIP Ubiquitylation K221 0.280 1.455 _EAAQEAVK(gl)LYNNHEIR_
SYNCRIP Ubiquitylation K315 -0.279 1.412 _LMSGKVK(gl)_
SYNCRIP Ubiquitylation K103 0.732 0.774 _SAFLCGVMK(gl)TYR_
SYNCRIP Ubiquitylation K313 1.171 0.697 _LMSGK(gl)VK_
SYNCRIP Ubiquitylation K363 -0.725 -0.190 _AFSQFGK(gl)LER_
SYNCRIP Ubiquitylation K111 -1.305 _QGTK(gl)VADSSKGPDEAK_
SYNCRIP Ubiquitylation K123 1.402 _VADSSKGPDEAK(gl)IK_

Background Information for SYNCRIP:


Pubmed-SYNCRIP »
Uniprot-SYNCRIP »
Biogrid-SYNCRIP »
ProteomicsDB-SYNCRIP »

Tumorportal-SYNCRIP »
COSMIC-SYNCRIP »
GenomeRNAi-SYNCRIP »
Genecards-SYNCRIP


Protein-protein Interactions for SYNCRIP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPD Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPH2 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait JUNB Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF21B Cat. description Hein, Mann, Cell 2015
Category members IP bait MRPL50 Cat. description Hein, Mann, Cell 2015
Category members IP bait NEDD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NFYC Cat. description Hein, Mann, Cell 2015
Category members IP bait PCDH7 Cat. description Hein, Mann, Cell 2015
Category members IP bait SORT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait TSNAX Cat. description Hein, Mann, Cell 2015
Category members IP bait APOBEC3D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC59 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELAVL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GAR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRMT8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait QKI Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SFPQ Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UTP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF169 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SYNCRIP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members HnRNP_R/Q_splicing_fac IPR006535 0


Protein complexes (CORUM database) featuring SYNCRIP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1181 C complex spliceosome Database 2.39
Category members Corum 5385 GAIT complex Database 1.27
Category members Corum 1307 Multiprotein complex (mRNA turnover) Database 0.21


Categories featuring SYNCRIP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0030529 ribonucleoprotein complex Database 8.45
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0070934 CRD-mediated mRNA stabilization Database 0.7
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0008143 poly(A) RNA binding Database 0.44
Category members GO Category GO:0070937 CRD-mediated mRNA stability complex Database 0.44
Category members GO Category GO:0017148 negative regulation of translation Database 0.34
Category members GO Category GO:0006396 RNA processing Database 0.17
Category members GO Category GO:0071346 cellular response to interferon-gamma Database 0.04
Category members GO Category GO:0071204 histone pre-mRNA 3'end processing complex Database 0


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