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Query: STX7

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
STX7 0 2.869 0.300 -0.680 -0.634 0.302

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
STX7 Ubiquitylation K138 0.339 1.363 _VSGSFPEDSSK(gl)ER_
STX7 Ubiquitylation K24 0.273 1.149 _ISSNIQK(gl)ITQCSVEIQR_
STX7 Phosphorylation S131 0.946 _VSGS(ph)FPEDSSK_
STX7 Phosphorylation S129 0.553 0.627 _VS(ph)GSFPEDSSK_
STX7 Phosphorylation T79 0.275 0.476 _EFGSLPTT(ph)PSEQR_
STX7 Phosphorylation S125 0.381 _AS(ph)SRVS(ph)GSFPEDSSK_
STX7 Phosphorylation S126 0.375 0.381 _ASS(ph)RVSGSFPEDSSK_
STX7 Phosphorylation T4 0.208 _(ac)SYT(ph)PGVGGDPAQLAQR_
STX7 Phosphorylation S2 -0.818 0.074 _(ac)S(ph)YTPGVGGDPAQLAQR_
STX7 Ubiquitylation K71 -1.063 -0.790 _ETDKYIK(gl)EFGSLPTTPSEQR_

Background Information for STX7:


Pubmed-STX7 »
Uniprot-STX7 »
Biogrid-STX7 »
ProteomicsDB-STX7 »

Tumorportal-STX7 »
COSMIC-STX7 »
GenomeRNAi-STX7 »
Genecards-STX7


Protein-protein Interactions for STX7
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait RNPS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SNAP29 Cat. description Hein, Mann, Cell 2015
Category members IP bait VAMP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait C1orf85 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ENPP6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GDPD5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GTF2E2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPAR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SEC13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SEC22B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STXBP6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM200A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAMP4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VTI1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in STX7
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members T_SNARE_dom IPR000727 0.54
Category members Syntaxin_N IPR006011 0.14
Category members t-SNARE IPR010989 0.04


Protein complexes (CORUM database) featuring STX7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 943 Class C Vps complex (VPS11, VPS18, STX7) Database 0


Categories featuring STX7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members Pathway Pathway_1261 KEGG_SNARE_INTERACTIONS_IN_VESICULAR_TRANSPORT 0 1.52
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0006892 post-Golgi vesicle-mediated transport Database 0.74
Category members GO Category GO:0031901 early endosome membrane Database 0.58
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0031201 SNARE complex Database 0.49
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members Pathway Pathway_1262 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS 0 0.2
Category members GO Category GO:0005484 SNAP receptor activity Database 0.2
Category members Pathway Pathway_1263 REACTOME_BOTULINUM_NEUROTOXICITY 0 0.07
Category members GO Category GO:0000149 SNARE binding Database 0.05
Category members Pathway Pathway_139 REACTOME_NEURONAL_SYSTEM 0 0
Category members GO Category GO:0016079 synaptic vesicle exocytosis Database 0


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