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Query: STK25

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
STK25 0 0.534 1.220 -0.770 -0.371 0.364
STK25 0 0.534 1.220 -0.770 -0.052

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
STK25 Phosphorylation S4 0.269 0.161 _(ac)AHS(ph)PVAVQVPGMQNNIADPEELFTK_
STK25 Ubiquitylation K162 -0.327 0.155 _GLDYLHSEKK(gl)_
STK25 Ubiquitylation K302 -0.101 0.068 _K(gl)TSYLTELIDR_
STK25 Ubiquitylation K197 -0.399 0.038 _LADFGVAGQLTDTQIK(gl)R_
STK25 Ubiquitylation K423 -0.470 -0.024 _SIAVAEAACPGITDKMVK(gl)_
STK25 Ubiquitylation K298 0.008 -0.419 _FIVK(gl)NSK_
STK25 Ubiquitylation K255 -0.986 _VLFLIPK(gl)NNPPTLVGDFTK_
STK25 Ubiquitylation K420 -0.470 _SIAVAEAACPGITDK(gl)MVK_

Background Information for STK25:


Pubmed-STK25 »
Uniprot-STK25 »
Biogrid-STK25 »
ProteomicsDB-STK25 »

Tumorportal-STK25 »
COSMIC-STK25 »
GenomeRNAi-STK25 »
Genecards-STK25


Protein-protein Interactions for STK25
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARL13B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C10orf47 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C4orf19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDCD10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STK25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in STK25
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring STK25
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring STK25
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0007163 establishment or maintenance of cell polarity Database 1.08
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0004702 receptor signaling protein serine/threonine kinase activity Database 0.1
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0006979 response to oxidative stress Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0045595 regulation of cell differentiation Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0050772 positive regulation of axonogenesis Database 0
Category members GO Category GO:0051645 Golgi localization Database 0


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