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Query: SSH2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SSH2 0 0.834 -0.270 0.300

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SSH2 Phosphorylation S514 0.350 0.184 _DITTS(ph)ADQIAEVK_

Background Information for SSH2:





Protein-protein Interactions for SSH2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF3A Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait TMOD3 Cat. description Hein, Mann, Cell 2015


Protein Domains in SSH2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DEK_C IPR014876 0.16
Category members Dual-sp_phosphatase_cat-dom IPR000340 0
Category members Tyr/Dual-sp_Pase IPR000387 0
Category members Dual-sp_phosphatase_subgr_cat IPR020422 0
Category members Prot-tyrosine_phosphatase-like IPR029021 0


Protein complexes (CORUM database) featuring SSH2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SSH2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0010591 regulation of lamellipodium assembly Database 0.31
Category members GO Category GO:0004721 phosphoprotein phosphatase activity Database 0.11
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members GO Category GO:0004725 protein tyrosine phosphatase activity Database 0
Category members GO Category GO:0006470 protein dephosphorylation Database 0
Category members GO Category GO:0008064 regulation of actin polymerization or depolymerization Database 0
Category members GO Category GO:0008138 protein tyrosine/serine/threonine phosphatase activity Database 0
Category members GO Category GO:0016311 dephosphorylation Database 0
Category members GO Category GO:0016791 phosphatase activity Database 0
Category members GO Category GO:0050770 regulation of axonogenesis Database 0


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