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Query: SSB

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SSB 0 -0.121 -0.280 0.190 -2.187 -0.343 0.023

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SSB Ubiquitylation K287 0.046 1.014 _AK(gl)DANNGNLQLR_
SSB Ubiquitylation K328 0.436 0.707 _IIEDQQESLNK(gl)WK_
SSB Ubiquitylation K276 0.992 0.682 _EGIILFK(gl)EK_
SSB Ubiquitylation K278 0.682 _EGIILFK(gl)EK_
SSB Phosphorylation S366 0.043 0.146 _FAS(ph)DDEHDEHDENGATGPVKR_
SSB Phosphorylation S94 -0.455 -0.863 _SPS(ph)KPLPEVTDEYKNDVK_
SSB Phosphorylation S92 -0.549 -0.960 _S(ph)PSKPLPEVTDEYK_
SSB Ubiquitylation K9 0.171 _(ac)AENGDNEK(gl)MAALEAK_
SSB Ubiquitylation K37 0.184 _DKFLK(gl)EQIK_
SSB Ubiquitylation K76 0.247 _SK(gl)AELMEISEDKTK_
SSB Ubiquitylation K88 -0.144 _AELMEISEDKTK(gl)IR_
SSB Ubiquitylation K166 0.281 _K(gl)FVETPGQK_
SSB Ubiquitylation K191 0.063 _DDYFAK(gl)K_
SSB Ubiquitylation K224 -0.359 _QKLEEDAEMK(gl)SLEEK_
SSB Ubiquitylation K269 -0.371 _GAK(gl)EGIILFK_
SSB Ubiquitylation K361 0.065 _GKVQFQGKK(gl)_

Background Information for SSB:


Pubmed-SSB »
Uniprot-SSB »
Biogrid-SSB »
ProteomicsDB-SSB »

Tumorportal-SSB »
COSMIC-SSB »
GenomeRNAi-SSB »
Genecards-SSB


Protein-protein Interactions for SSB
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARMC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait BSDC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CASC5 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCNA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MPHOSPH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MRPL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKCI Cat. description Hein, Mann, Cell 2015
Category members IP bait SNCA Cat. description Hein, Mann, Cell 2015
Category members IP bait TBC1D9 Cat. description Hein, Mann, Cell 2015
Category members IP bait TRIM33 Cat. description Hein, Mann, Cell 2015
Category members IP bait HIST1H1E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SURF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRMT2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SSB
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members Lupus_La IPR002344 0
Category members Lupus_La_RNA-bd IPR006630 0
Category members RRM_3 IPR014886 0


Protein complexes (CORUM database) featuring SSB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1223 H2AX complex, isolated from cells without IR exposure Database 8.51
Category members Corum 5613 Emerin complex 25 Database 0.04


Categories featuring SSB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members GO Category GO:0030529 ribonucleoprotein complex Database 8.45
Category members Pathway Pathway_350 REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION 0 7.97
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0003729 mRNA binding Database 1.38
Category members Pathway Pathway_889 KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS 0 0.9
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members Pathway Pathway_353 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION 0 0.29
Category members Pathway Pathway_357 REACTOME_RNA_POL_III_TRANSCRIPTION 0 0.29
Category members GO Category GO:0006400 tRNA modification Database 0.25
Category members GO Category GO:0006396 RNA processing Database 0.17
Category members GO Category GO:0000049 tRNA binding Database 0
Category members GO Category GO:0008334 histone mRNA metabolic process Database 0


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