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Query: SS18

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SS18 0 -0.079 0.150 -0.700 -0.079 -1.091 0.600

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for SS18:


Pubmed-SS18 »
Uniprot-SS18 »
Biogrid-SS18 »
ProteomicsDB-SS18 »

Tumorportal-SS18 »
COSMIC-SS18 »
GenomeRNAi-SS18 »
Genecards-SS18


Protein-protein Interactions for SS18
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDKN1A Cat. description Hein, Mann, Cell 2015
Category members IP bait NEFM Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait WASH3P Cat. description Hein, Mann, Cell 2015
Category members IP bait BCL7A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BCL7C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DPF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DPF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SMARCE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SS18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SS18
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SS18_fam IPR007726 0


Protein complexes (CORUM database) featuring SS18
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SS18
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0000226 microtubule cytoskeleton organization Database 0.5
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity Database 0.12
Category members GO Category GO:0005881 cytoplasmic microtubule Database 0.04
Category members Disease phenotype Synovial_sarcoma Synovial sarcoma Database 0
Category members GO Category GO:0000902 cell morphogenesis Database 0
Category members GO Category GO:0007010 cytoskeleton organization Database 0
Category members GO Category GO:0048013 ephrin receptor signaling pathway Database 0


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