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Query: SRGAP2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SRGAP2 0 -0.349

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SRGAP2 Ubiquitylation K33 -0.066 _AQLTEQMK(gl)CLDQQCELR_
SRGAP2 Phosphorylation S1061 -0.109 -0.174 _TNATS(ph)PGVNSSTS(ph)PQSTDK_
SRGAP2 Ubiquitylation K381 -0.208 _LSTLK(gl)IENEEVKK_
SRGAP2 Phosphorylation S1053 -0.109 -0.231 _TNATS(ph)PGVNSSTS(ph)PQSTDK_
SRGAP2 Ubiquitylation K182 -0.693 _TYHM(ox)YNADSISAQSKLK(gl)_
SRGAP2 Ubiquitylation K245 -0.743 _YTENKLK(gl)_
SRGAP2 Ubiquitylation K438 -1.020 _STVSETFMSKPSIAK(gl)R_

Background Information for SRGAP2:


Pubmed-SRGAP2 »
Uniprot-SRGAP2 »
Biogrid-SRGAP2 »
ProteomicsDB-SRGAP2 »

Tumorportal-SRGAP2 »
COSMIC-SRGAP2 »
GenomeRNAi-SRGAP2 »
Genecards-SRGAP2


Protein-protein Interactions for SRGAP2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait SRGAP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIML2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SRGAP2
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring SRGAP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SRGAP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0045335 phagocytic vesicle Database 0.16
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0048365 Rac GTPase binding Database 0.1
Category members GO Category GO:0045211 postsynaptic membrane Database 0.06
Category members Pathway Pathway_1034 KEGG_AXON_GUIDANCE 0 0.04
Category members Pathway Pathway_1031 REACTOME_SIGNALING_BY_ROBO_RECEPTOR 0 0
Category members Pathway Pathway_519 REACTOME_SIGNALING_BY_RHO_GTPASES 0 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0014069 postsynaptic density Database 0
Category members GO Category GO:0030675 Rac GTPase activator activity Database 0
Category members GO Category GO:0032855 positive regulation of Rac GTPase activity Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0046847 filopodium assembly Database 0
Category members GO Category GO:0048812 neuron projection morphogenesis Database 0
Category members GO Category GO:0060996 dendritic spine development Database 0


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