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Query: SORBS3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SORBS3 0 0.299

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SORBS3 Phosphorylation S258 -0.155 0.017 _HPS(ph)SPSALR_
SORBS3 Phosphorylation S6 0.282 -0.078 _(ac)ADGGS(ph)PFLGRR_
SORBS3 Phosphorylation S259 -0.175 -0.164 _HPSS(ph)PSALR_
SORBS3 Phosphorylation S244 -0.506 -0.252 _LCDDGPQLPTS(ph)PR_
SORBS3 Phosphorylation T276 -0.389 -0.280 _SPADPTDLGGQT(ph)SPRR_
SORBS3 Phosphorylation S277 -0.371 -0.339 _SPADPTDLGGQTS(ph)PRR_
SORBS3 Phosphorylation T243 -0.650 -0.441 _LCDDGPQLPT(ph)SPR_
SORBS3 Phosphorylation S109 -1.018 _LKFDFQAQS(ph)PK_

Background Information for SORBS3:


Pubmed-SORBS3 »
Uniprot-SORBS3 »
Biogrid-SORBS3 »
ProteomicsDB-SORBS3 »

Tumorportal-SORBS3 »
COSMIC-SORBS3 »
GenomeRNAi-SORBS3 »
Genecards-SORBS3


Protein-protein Interactions for SORBS3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANAPC15 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC22 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC23 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC26 Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait KATNA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KRAS Cat. description Hein, Mann, Cell 2015
Category members IP bait SGOL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SIN3A Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait LRFN4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SORBS3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SH3_2 IPR011511 0.08
Category members SH3_domain IPR001452 0
Category members Sorb IPR003127 0
Category members Spectrin_alpha_SH3 IPR013315 0


Protein complexes (CORUM database) featuring SORBS3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SORBS3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0017166 vinculin binding Database 1.01
Category members GO Category GO:0005925 focal adhesion Database 0.68
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0007015 actin filament organization Database 0.08
Category members GO Category GO:0043410 positive regulation of MAPK cascade Database 0.06
Category members GO Category GO:0031589 cell-substrate adhesion Database 0.04
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members Pathway Pathway_949 REACTOME_SMOOTH_MUSCLE_CONTRACTION 0 0
Category members Pathway Pathway_950 REACTOME_MUSCLE_CONTRACTION 0 0
Category members GO Category GO:0005200 structural constituent of cytoskeleton Database 0
Category members GO Category GO:0006936 muscle contraction Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0051495 positive regulation of cytoskeleton organization Database 0
Category members GO Category GO:0051496 positive regulation of stress fiber assembly Database 0


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