bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: SLC12A2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SLC12A2 1 3.831 -0.590 1.190 -0.386 -0.263

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SLC12A2 Ubiquitylation K958 1.077 1.080 _DVVVSVEYSK(gl)K_
SLC12A2 Ubiquitylation K959 1.579 1.080 _DVVVSVEYSKK(gl)_
SLC12A2 Ubiquitylation K841 -0.060 0.706 _EMSIDQAK(gl)YQR_
SLC12A2 Ubiquitylation K948 1.471 0.675 _SPGTK(gl)DVVVSVEYSK_
SLC12A2 Phosphorylation S944 0.525 _LKEGLDISHLQGQEELLSSQEKS(ph)PGTK_
SLC12A2 Ubiquitylation K833 0.031 0.510 _QAMK(gl)EMSIDQAK_
SLC12A2 Ubiquitylation K991 1.299 0.502 _TATQPLLK(gl)K_
SLC12A2 Ubiquitylation K280 -0.876 0.485 _DAVVTYTAESK(gl)GVVK_
SLC12A2 Ubiquitylation K995 1.109 0.084 _ESK(gl)GPIVPLNVADQK_
SLC12A2 Ubiquitylation K971 1.154 -0.324 _KSDLDTSKPLSEK(gl)PITHK_
SLC12A2 Phosphorylation S994 0.106 -0.409 _KES(ph)KGPIVPLNVADQK_
SLC12A2 Phosphorylation S79 -0.757 _DGGGVRDEGPAAAGDGLGRPLGPTPSQS(ph)R_
SLC12A2 Ubiquitylation K136 -0.018 _QTPADGEASGESEPAKGSEEAK(gl)GR_
SLC12A2 Ubiquitylation K284 -0.876 _DAVVTYTAESK(gl)GVVK_
SLC12A2 Ubiquitylation K966 1.102 _KSDLDTSK(gl)PLSEKPITHK_
SLC12A2 Ubiquitylation K983 0.798 _VEEEDGK(gl)TATQPLLKK_
SLC12A2 Ubiquitylation K992 1.045 _K(gl)ESKGPIVPLNVADQK_
SLC12A2 Ubiquitylation K1018 0.796 _LLEASTQFQKK(gl)_

Background Information for SLC12A2:


Pubmed-SLC12A2 »
Uniprot-SLC12A2 »
Biogrid-SLC12A2 »
ProteomicsDB-SLC12A2 »

Tumorportal-SLC12A2 »
COSMIC-SLC12A2 »
GenomeRNAi-SLC12A2 »
Genecards-SLC12A2


Protein-protein Interactions for SLC12A2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait BACH1 Cat. description Hein, Mann, Cell 2015
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait C1QBP Cat. description Hein, Mann, Cell 2015
Category members IP bait CDKN2AIP Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPE Cat. description Hein, Mann, Cell 2015
Category members IP bait HTR3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS9C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTGIR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMED6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SLC12A2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Na/K/Cl_cotranspt IPR002443 0.17
Category members Na/K/Cl_cotransptS IPR004842 0.09
Category members AA-permease/SLC12A_dom IPR004841 0.08
Category members AA_permease_N IPR013612 0


Protein complexes (CORUM database) featuring SLC12A2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SLC12A2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0050910 detection of mechanical stimulus involved in sensory perception of sound Database 0.7
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_187 KEGG_VIBRIO_CHOLERAE_INFECTION 0 0.44
Category members Pathway Pathway_96 REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 0 0.23
Category members GO Category GO:0006811 ion transport Database 0.18
Category members GO Category GO:0008511 sodium:potassium:chloride symporter activity Database 0.17
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0006813 potassium ion transport Database 0.11
Category members GO Category GO:0006814 sodium ion transport Database 0.09
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0035264 multicellular organism growth Database 0.04
Category members GO Category GO:0016323 basolateral plasma membrane Database 0.04
Category members GO Category GO:0015377 cation:chloride symporter activity Database 0.03
Category members Pathway Pathway_1207 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES 0 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0006821 chloride transport Database 0
Category members GO Category GO:0006972 hyperosmotic response Database 0
Category members GO Category GO:0007214 gamma-aminobutyric acid signaling pathway Database 0
Category members GO Category GO:0015696 ammonium transport Database 0
Category members GO Category GO:0016324 apical plasma membrane Database 0
Category members GO Category GO:0030321 transepithelial chloride transport Database 0
Category members GO Category GO:0051739 ammonia transmembrane transporter activity Database 0
Category members GO Category GO:0060444 branching involved in mammary gland duct morphogenesis Database 0
Category members GO Category GO:0060763 mammary duct terminal end bud growth Database 0
Category members GO Category GO:0070634 transepithelial ammonium transport Database 0


.

© Copyright Svejstrup Laboratory 2015