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Query: SKIV2L

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SKIV2L 1 4.782 -1.520 3.780 -0.001 -0.057

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SKIV2L Phosphorylation S256 0.435 0.585 _ASS(ph)LEDLVLK_
SKIV2L Phosphorylation S255 0.352 0.534 _AS(ph)SLEDLVLK_
SKIV2L Phosphorylation S245 -0.192 0.456 _GDTVSAS(ph)PCSAPLAR_
SKIV2L Ubiquitylation K720 -0.315 _GLDPTGTVILLCK(gl)GR_
SKIV2L Ubiquitylation K1075 -0.404 _TLGYVDEAGTVK(gl)LAGR_
SKIV2L Ubiquitylation K526 -0.595 _GYYAAVEAKK(gl)_
SKIV2L Ubiquitylation K791 0.355 -0.629 _AHEQALAELTK(gl)R_
SKIV2L Ubiquitylation K369 -0.901 _ALSNQK(gl)FR_

Background Information for SKIV2L:


Pubmed-SKIV2L »
Uniprot-SKIV2L »
Biogrid-SKIV2L »
ProteomicsDB-SKIV2L »

Tumorportal-SKIV2L »
COSMIC-SKIV2L »
GenomeRNAi-SKIV2L »
Genecards-SKIV2L


Protein-protein Interactions for SKIV2L
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EIF3A Cat. description Hein, Mann, Cell 2015
Category members IP bait NPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB4B Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015


Protein Domains in SKIV2L
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase_C IPR001650 2.48
Category members Helicase_ATP-bd IPR014001 2.48
Category members DEAD/DEAH_box_helicase_dom IPR011545 0.35
Category members DSH_C IPR012961 0
Category members RNA_helicase_ATP-dep_SK12/DOB1 IPR016438 0


Protein complexes (CORUM database) featuring SKIV2L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1168 SKI complex Database 0.11


Categories featuring SKIV2L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Database 1.64
Category members GO Category GO:0004004 ATP-dependent RNA helicase activity Database 1.43
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008026 ATP-dependent helicase activity Database 0.79
Category members Pathway Pathway_310 KEGG_RNA_DEGRADATION 0 0.26
Category members GO Category GO:0055087 Ski complex Database 0.11
Category members GO Category GO:0016817 hydrolase activity, acting on acid anhydrides Database 0.06
Category members Disease phenotype Syndromic_diarrhea Syndromic diarrhea Database 0


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