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Query: SIN3B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SIN3B 0 1.323 0.040 -0.220 0.475 0.416

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SIN3B Phosphorylation S1003 0.432 _YVEQYVGTEGASSS(ph)PTEGFLLKPVFLQR_

Background Information for SIN3B:


Pubmed-SIN3B »
Uniprot-SIN3B »
Biogrid-SIN3B »
ProteomicsDB-SIN3B »

Tumorportal-SIN3B »
COSMIC-SIN3B »
GenomeRNAi-SIN3B »
Genecards-SIN3B


Protein-protein Interactions for SIN3B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GATAD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO5C Cat. description Hein, Mann, Cell 2015
Category members IP bait PHF12 Cat. description Hein, Mann, Cell 2015
Category members IP bait SAP30 Cat. description Hein, Mann, Cell 2015
Category members IP bait SIN3B Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM60A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HDAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ING2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MORF4L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PHF23 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBBP7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUDS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SIN3B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members HDAC_interact IPR013194 0.08
Category members PAH IPR003822 0


Protein complexes (CORUM database) featuring SIN3B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 888 MTA2 complex Database 2.24
Category members Corum 632 Anti-HDAC2 complex Database 2.11
Category members Corum 2721 HCF-1 complex Database 2.08
Category members Corum 3167 NCOR-SIN3-HDAC-HESX1 complex Database 0.94
Category members Corum 696 BRMS1-SIN3-HDAC complex Database 0.66
Category members Corum 745 NCOR-SIN3-RPD3 complex Database 0.47


Categories featuring SIN3B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members Pathway Pathway_881 PID_TELOMERASE_PATHWAY 0 2.64
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members Pathway Pathway_943 PID_HDAC_CLASSI_PATHWAY 0 1.08
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0001741 XY body Database 0.47
Category members Pathway Pathway_845 PID_SMAD2_3NUCLEAR_PATHWAY 0 0.46
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_1 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 0 0.23
Category members Pathway Pathway_984 PID_HEDGEHOG_GLI_PATHWAY 0 0.1
Category members Pathway Pathway_1097 BIOCARTA_ETS_PATHWAY 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members GO Category GO:0000805 X chromosome Database 0
Category members GO Category GO:0000806 Y chromosome Database 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007519 skeletal muscle tissue development Database 0
Category members GO Category GO:0030849 autosome Database 0
Category members GO Category GO:0044255 cellular lipid metabolic process Database 0
Category members GO Category GO:0048738 cardiac muscle tissue development Database 0


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