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Query: SENP3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SENP3 0 1.744 -0.730 0.550 0.242 0.595

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SENP3 Ubiquitylation K505 -0.150 _YLQAEAVK(gl)K_
SENP3 Ubiquitylation K506 -0.150 _YLQAEAVK(gl)K_
SENP3 Phosphorylation S169 -0.526 -0.554 _NHLS(ph)PQQGGATPQVPSPCCR_
SENP3 Phosphorylation S181 1.061 -0.600 _NHLSPQQGGATPQVPS(ph)PCCR_
SENP3 Phosphorylation S212 -1.048 _LGLLGALMAEDGVRGS(ph)PPVPSGPPMEEDGLR_

Background Information for SENP3:


Pubmed-SENP3 »
Uniprot-SENP3 »
Biogrid-SENP3 »
ProteomicsDB-SENP3 »

Tumorportal-SENP3 »
COSMIC-SENP3 »
GenomeRNAi-SENP3 »
Genecards-SENP3


Protein-protein Interactions for SENP3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DAXX Cat. description Hein, Mann, Cell 2015
Category members IP bait NOL9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PHF19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF13B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SENP3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Peptidase_C48 IPR003653 0


Protein complexes (CORUM database) featuring SENP3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5386 MLL1-WDR5 complex Database 0.31


Categories featuring SENP3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0004843 ubiquitin-specific protease activity Database 3.28
Category members GO Category GO:0071339 MLL1 complex Database 0.45
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0008234 cysteine-type peptidase activity Database 0
Category members GO Category GO:0019538 protein metabolic process Database 0


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