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Query: SEMA6A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SEMA6A 0 -0.265 0.490 0.020

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SEMA6A Ubiquitylation K259 -0.265 _VAQVCK(gl)NDMGGSQR_

Background Information for SEMA6A:


Pubmed-SEMA6A »
Uniprot-SEMA6A »
Biogrid-SEMA6A »
ProteomicsDB-SEMA6A »

Tumorportal-SEMA6A »
COSMIC-SEMA6A »
GenomeRNAi-SEMA6A »
Genecards-SEMA6A


Protein-protein Interactions for SEMA6A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ADAM30 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait INSL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ITM2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MPPE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHGA5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTCH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SEMA6A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Semap_dom IPR001627 0.04
Category members Plexin_repeat IPR002165 0
Category members Plexin-like_fold IPR016201 0


Protein complexes (CORUM database) featuring SEMA6A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SEMA6A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members Pathway Pathway_674 REACTOME_SEMAPHORIN_INTERACTIONS 0 0.96
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0030424 axon Database 0.23
Category members GO Category GO:0004888 transmembrane signaling receptor activity Database 0.15
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0007166 cell surface receptor signaling pathway Database 0.1
Category members Pathway Pathway_1284 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS 0 0.04
Category members Pathway Pathway_1034 KEGG_AXON_GUIDANCE 0 0.04
Category members GO Category GO:0001764 neuron migration Database 0
Category members GO Category GO:0004872 receptor activity Database 0
Category members GO Category GO:0007010 cytoskeleton organization Database 0
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0009887 organ morphogenesis Database 0
Category members GO Category GO:0030215 semaphorin receptor binding Database 0
Category members GO Category GO:0051642 centrosome localization Database 0


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