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Query: RRN3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RRN3 1 2.656 -2.020 3.080 -0.424
RRN3 1 2.656 0.540 -0.250 -0.424

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for RRN3:


Pubmed-RRN3 »
Uniprot-RRN3 »
Biogrid-RRN3 »
ProteomicsDB-RRN3 »

Tumorportal-RRN3 »
COSMIC-RRN3 »
GenomeRNAi-RRN3 »
Genecards-RRN3


Protein-protein Interactions for RRN3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait POLR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR1C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM108 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TWISTNB Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RRN3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26


Protein complexes (CORUM database) featuring RRN3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1558 POLR1B-RRN3 complex Database 0.29
Category members Corum 1557 NMI-POLR1B-RRN3 complex Database 0.08


Categories featuring RRN3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005488 binding Database 9.32
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_351 REACTOME_RNA_POL_I_TRANSCRIPTION 0 8.31
Category members Pathway Pathway_350 REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION 0 7.97
Category members GO Category GO:0006352 DNA-dependent transcription, initiation Database 3.76
Category members Pathway Pathway_346 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION 0 3.42
Category members GO Category GO:0006360 transcription from RNA polymerase I promoter Database 2.66
Category members GO Category GO:0006361 transcription initiation from RNA polymerase I promoter Database 2.41
Category members Pathway Pathway_724 PID_MTOR_4PATHWAY 0 2
Category members GO Category GO:0003743 translation initiation factor activity Database 0.71
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0042254 ribosome biogenesis Database 0.29
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0007000 nucleolus organization Database 0.18
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0048872 homeostasis of number of cells Database 0.05
Category members GO Category GO:0007028 cytoplasm organization Database 0
Category members GO Category GO:0070063 RNA polymerase binding Database 0


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