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Query: RPL11

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RPL11 0 3.208 -0.210 0.230 0.115 0.398 0.883 -0.361 -0.495

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RPL11 Ubiquitylation K145 -0.291 1.240 _PGFSIADKK(gl)R_
RPL11 Ubiquitylation K78 1.198 0.854 _GAK(gl)AEEILEK_
RPL11 Ubiquitylation K144 0.153 0.622 _PGFSIADK(gl)K_
RPL11 Ubiquitylation K67 0.460 0.343 _NEK(gl)IAVHCTVR_
RPL11 Ubiquitylation K159 -0.008 0.322 _ISK(gl)EEAMR_
RPL11 Ubiquitylation K88 0.295 _AEEILEKGLK(gl)_
RPL11 Ubiquitylation K85 -0.347 0.145 _AEEILEK(gl)GLK_
RPL11 Ubiquitylation K52 0.253 0.130 _VLEQLTGQTPVFSK(gl)AR_
RPL11 Ubiquitylation K169 -0.196 _WFQQK(gl)YDGIILPGK_
RPL11 Ubiquitylation K178 -0.182 -0.325 _YDGIILPGK(gl)_
RPL11 Ubiquitylation K8 -0.287 -0.982 _(ac)AQDQGEK(gl)ENPM(ox)R_
RPL11 Ubiquitylation K154 0.904 _TGCIGAK(gl)HR_

Background Information for RPL11:


Pubmed-RPL11 »
Uniprot-RPL11 »
Biogrid-RPL11 »
ProteomicsDB-RPL11 »

Tumorportal-RPL11 »
COSMIC-RPL11 »
GenomeRNAi-RPL11 »
Genecards-RPL11


Protein-protein Interactions for RPL11
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BRWD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3A Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3E Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait NAA50 Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait NPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHIT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CNBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SURF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RPL11
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring RPL11
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3055 Nop56p-associated pre-rRNA complex Database INF
Category members Corum 306 Ribosome, cytoplasmic Database INF
Category members Corum 308 60S ribosomal subunit, cytoplasmic Database INF
Category members Corum 5380 TRBP containing complex (DICER, RPL7A, EIF6, MOV10 and subunits of the 60S ribosomal particle) Database 5.3


Categories featuring RPL11
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_369 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION 0 INF
Category members Pathway Pathway_371 REACTOME_INFLUENZA_LIFE_CYCLE 0 INF
Category members Pathway Pathway_456 REACTOME_TRANSLATION 0 INF
Category members Pathway Pathway_459 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE 0 INF
Category members Pathway Pathway_768 REACTOME_PEPTIDE_CHAIN_ELONGATION 0 INF
Category members Pathway Pathway_770 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX 0 INF
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members Pathway Pathway_772 KEGG_RIBOSOME 0 INF
Category members Pathway Pathway_773 REACTOME_METABOLISM_OF_MRNA 0 INF
Category members Pathway Pathway_774 REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION 0 INF
Category members GO Category GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Database INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0003735 structural constituent of ribosome Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0006413 translational initiation Database INF
Category members GO Category GO:0006414 translational elongation Database INF
Category members GO Category GO:0006415 translational termination Database INF
Category members GO Category GO:0006614 SRP-dependent cotranslational protein targeting to membrane Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members GO Category GO:0019058 viral life cycle Database INF
Category members GO Category GO:0019083 viral transcription Database INF
Category members GO Category GO:0022625 cytosolic large ribosomal subunit Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005840 ribosome Database 12.2
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0006364 rRNA processing Database 2.47
Category members Disease phenotype Blackfan-Diamond_anemia Blackfan-Diamond anemia Database 2.38
Category members Pathway Pathway_416 PID_P53_REGULATION_PATHWAY 0 2.29
Category members Pathway Pathway_65 PID_MYC_ACTIV_PATHWAY 0 1.08
Category members GO Category GO:0042273 ribosomal large subunit biogenesis Database 0.59
Category members GO Category GO:0019843 rRNA binding Database 0.46
Category members GO Category GO:0006605 protein targeting Database 0.29
Category members GO Category GO:0034504 protein localization to nucleus Database 0.15


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