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Query: RNASEH2A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RNASEH2A 0 0.685 0.140 0.630 1.183

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RNASEH2A Ubiquitylation K64 -0.163 -0.965 _LADLEALK(gl)VADSK_
RNASEH2A Ubiquitylation K69 -1.087 _VADSK(gl)TLLESERER_

Background Information for RNASEH2A:





Protein-protein Interactions for RNASEH2A

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RNASEH2A Cat. description Hein, Mann, Cell 2015
Category members IP bait RNASEH2B Cat. description Hein, Mann, Cell 2015
Category members IP bait AGPAT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BPNT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C6orf141 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM136A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KPTN Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RNASEH2A

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RNaseH-like_dom IPR012337 0


Protein complexes (CORUM database) featuring RNASEH2A

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RNASEH2A

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0006260 DNA replication Database 3.34
Category members Pathway Pathway_329 KEGG_DNA_REPLICATION 0 0.95
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members Disease phenotype Aicardi-Goutieres_Syndrome Aicardi-Goutieres Syndrome Database 0.05
Category members GO Category GO:0032299 ribonuclease H2 complex Database 0.02
Category members GO Category GO:0004523 ribonuclease H activity Database 0
Category members GO Category GO:0004540 ribonuclease activity Database 0
Category members GO Category GO:0006401 RNA catabolic process Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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