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Query: RHOU

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RHOU 0 -0.507 0.620 -1.000

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RHOU Ubiquitylation K248 -0.507 _NLSK(gl)SWWK_

Background Information for RHOU:


Pubmed-RHOU »
Uniprot-RHOU »
Biogrid-RHOU »
ProteomicsDB-RHOU »

Tumorportal-RHOU »
COSMIC-RHOU »
GenomeRNAi-RHOU »
Genecards-RHOU


Protein-protein Interactions for RHOU
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait IFNGR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IP6K2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RHOU
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Ran_GTPase IPR002041 1.25
Category members Small_GTPase_Ras IPR020849 0.7
Category members Small_GTPase_Rho IPR003578 0.65
Category members Small_GTPase IPR001806 0.65
Category members Small_GTPase_Rab_type IPR003579 0.51
Category members MIRO-like IPR013684 0.4
Category members Small_GTP-bd_dom IPR005225 0.32


Protein complexes (CORUM database) featuring RHOU
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RHOU
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0006913 nucleocytoplasmic transport Database 2.96
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0000082 G1/S transition of mitotic cell cycle Database 1.23
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members GO Category GO:0005925 focal adhesion Database 0.68
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0002102 podosome Database 0.3
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members Pathway Pathway_290 WNT_SIGNALING 0 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0007010 cytoskeleton organization Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0008360 regulation of cell shape Database 0
Category members GO Category GO:0016601 Rac protein signal transduction Database 0
Category members GO Category GO:0042995 cell projection Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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