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Query: RFFL

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RFFL 0 1.847 0.680 -0.480

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RFFL Phosphorylation S240 0.527 1.050 _RAS(ph)LSDLTDLEDIEGLTVR_
RFFL Phosphorylation S242 0.797 _RASLS(ph)DLTDLEDIEGLTVR_

Background Information for RFFL:





Protein-protein Interactions for RFFL

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RFFL Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RFFL

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_FYVE_PHD IPR011011 1.23
Category members Znf_RING IPR001841 0


Protein complexes (CORUM database) featuring RFFL

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RFFL

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0031625 ubiquitin protein ligase binding Database 2.54
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0002039 p53 binding Database 2.06
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process Database 0.23
Category members GO Category GO:0016023 cytoplasmic membrane-bounded vesicle Database 0.17
Category members GO Category GO:0010762 regulation of fibroblast migration Database 0.03
Category members Pathway Pathway_738 PID_TNF_PATHWAY 0 0
Category members GO Category GO:0002020 protease binding Database 0
Category members GO Category GO:0010008 endosome membrane Database 0
Category members GO Category GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway Database 0
Category members GO Category GO:0032006 regulation of TOR signaling Database 0
Category members GO Category GO:0070936 protein K48-linked ubiquitination Database 0


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