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Query: RDX

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RDX 1 0.593 0.060 -0.140 2.501 -2.209 0.246 0.091
RDX 1 0.593 0.060 -0.140 -0.243 -0.126 0.558

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RDX Ubiquitylation K162 1.580 0.660 _VMDQHK(gl)LTR_
RDX Ubiquitylation K162 1.465 0.362 _VLEQHK(gl)LTK_
RDX Ubiquitylation K139 1.519 0.361 _FGDYNK(gl)EVHK_
RDX Ubiquitylation K344 0.598 0.235 _EK(gl)EELMLR_
RDX Ubiquitylation K450 0.393 0.174 _AK(gl)EAQDDLVK_
RDX Ubiquitylation K79 0.172 -0.032 _ENPLQFK(gl)FR_
RDX Ubiquitylation K3 -0.313 -0.251 _PK(gl)PINVR_
RDX Ubiquitylation K165 1.017 _LTK(gl)EQWEER_
RDX Ubiquitylation K211 1.467 _IAQDLEMYGVNYFEIKNK(gl)_
RDX Ubiquitylation K352 0.222 _LK(gl)QIEEQTIK_
RDX Ubiquitylation K400 -0.067 _AAEEAK(gl)SAIAK_
RDX Ubiquitylation K405 1.145 _SAIAK(gl)QAADQMK_
RDX Ubiquitylation K435 0.279 _IALLEEAK(gl)K_
RDX Ubiquitylation K436 0.279 _IALLEEAK(gl)K_
RDX Ubiquitylation K526 0.583 _K(gl)QLQALSSELAQAR_
RDX Ubiquitylation K253 -0.069 _NISFNDK(gl)K_
RDX Ubiquitylation K263 -0.786 _K(gl)APDFVFYAPR_
RDX Ubiquitylation K357 -0.003 _LQDYEEK(gl)TK_
RDX Ubiquitylation K359 0.051 _LQDYEEK(gl)TK_

Background Information for RDX:


Pubmed-RDX »
Uniprot-RDX »
Biogrid-RDX »
ProteomicsDB-RDX »

Tumorportal-RDX »
COSMIC-RDX »
GenomeRNAi-RDX »
Genecards-RDX


Protein-protein Interactions for RDX
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EZR Cat. description Hein, Mann, Cell 2015
Category members IP bait MSN Cat. description Hein, Mann, Cell 2015
Category members IP bait C19orf21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RDX
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members Ez/rad/moesin_like IPR000798 0.38
Category members FERM_N IPR018979 0.36
Category members FERM_PH-like_C IPR018980 0.35
Category members Band_41_fam IPR019750 0.33
Category members FERM_domain IPR000299 0
Category members Moesin_tail IPR008954 0
Category members ERM IPR011174 0
Category members ERM_C_dom IPR011259 0
Category members Adenylate_cyclase-assoc_CAP_N IPR013992 0
Category members FERM_central IPR019748 0
Category members Band_41_domain IPR019749 0


Protein complexes (CORUM database) featuring RDX
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RDX
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0032154 cleavage furrow Database 2.01
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members Pathway Pathway_1075 REACTOME_L1CAM_INTERACTIONS 0 1.32
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members GO Category GO:0005925 focal adhesion Database 0.68
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0008092 cytoskeletal protein binding Database 0.5
Category members GO Category GO:0001726 ruffle Database 0.33
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0030033 microvillus assembly Database 0.23
Category members GO Category GO:0005902 microvillus Database 0.13
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members GO Category GO:0030175 filopodium Database 0.05
Category members Pathway Pathway_1136 REACTOME_RECYCLING_PATHWAY_OF_L1 0 0.04
Category members Disease phenotype Autosomal_recessive_nonsyndromic_sensorineural_deafness_type_DFNB Autosomal recessive nonsyndromic sensorineural deafness type DFNB Database 0.04
Category members Pathway Pathway_658 ST_GA13_PATHWAY 0 0
Category members Pathway Pathway_668 PID_RHOA_PATHWAY 0 0
Category members GO Category GO:0007010 cytoskeleton organization Database 0
Category members GO Category GO:0019898 extrinsic to membrane Database 0
Category members GO Category GO:0030315 T-tubule Database 0
Category members GO Category GO:0032420 stereocilium Database 0
Category members GO Category GO:0045176 apical protein localization Database 0
Category members GO Category GO:0045177 apical part of cell Database 0
Category members GO Category GO:0051286 cell tip Database 0
Category members GO Category GO:0051693 actin filament capping Database 0


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