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Query: RCOR1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RCOR1 2 7.782 -1.890 3.100 0.185 -0.123 0.523 0.896 0.794

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RCOR1 Phosphorylation S124 0.641 _S(ph)QERDNLGMLVWSPNQNLSEAK_
RCOR1 Phosphorylation S257 -0.356 _REREES(ph)EDELEEANGNNPIDIEVDQNK_
RCOR1 Ubiquitylation K156 1.766 _LDEYIAIAKEK(gl)_

Background Information for RCOR1:


Pubmed-RCOR1 »
Uniprot-RCOR1 »
Biogrid-RCOR1 »
ProteomicsDB-RCOR1 »

Tumorportal-RCOR1 »
COSMIC-RCOR1 »
GenomeRNAi-RCOR1 »
Genecards-RCOR1


Protein-protein Interactions for RCOR1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HMG20A Cat. description Hein, Mann, Cell 2015
Category members IP bait ARRDC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CTBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCAF12L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DOK4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ECE2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HDAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HMG20A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HMG20B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LLGL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNAI1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZSCAN5A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RCOR1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SANT/Myb IPR001005 2.18
Category members ELM2_dom IPR000949 0.51
Category members Antifreeze_1 IPR000104 0.24
Category members Homeodomain-like IPR009057 0


Protein complexes (CORUM database) featuring RCOR1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 642 CtBP complex Database 3.6
Category members Corum 646 HDAC1-associated protein complex Database 3.34
Category members Corum 649 HDAC1-associated core complex cII Database 3.34
Category members Corum 632 Anti-HDAC2 complex Database 2.11
Category members Corum 5614 Emerin complex 32 Database 1.48
Category members Corum 643 CtBP core complex Database 1.41
Category members Corum 648 HDAC1-associated core complex cI Database 0.75
Category members Corum 633 anti-BHC110 complex Database 0.53
Category members Corum 636 BHC complex Database 0.53
Category members Corum 1492 BHC110 complex Database 0.39
Category members Corum 620 CoREST-HDAC complex Database 0.34
Category members Corum 871 BRAF53-BRCA2 complex Database 0.34
Category members Corum 1233 CoREST-HDAC2 complex Database 0.32
Category members Corum 624 LSD1-CoREST complex Database 0.31
Category members Corum 626 LSD1 complex Database 0.17
Category members Corum 1232 REST-CoREST-mSIN3A complex Database 0.08


Categories featuring RCOR1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members Pathway Pathway_32 KEGG_HUNTINGTONS_DISEASE 0 0.46
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0070933 histone H4 deacetylation Database 0.37
Category members GO Category GO:0017053 transcriptional repressor complex Database 0.28
Category members GO Category GO:0045654 positive regulation of megakaryocyte differentiation Database 0.28
Category members GO Category GO:0030218 erythrocyte differentiation Database 0.13
Category members Pathway Pathway_385 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 0 0.07
Category members GO Category GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Database 0.04
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0


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