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Query: RCC1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RCC1 0 0.927 -0.180 0.240 -0.398 0.623 -0.380 0.480 0.104

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RCC1 Ubiquitylation K362 0.749 0.361 _LPAVSSVACGASVGYAVTK(gl)DGR_
RCC1 Ubiquitylation K232 0.594 0.184 _CVMLK(gl)SR_
RCC1 Ubiquitylation K335 -0.717 -0.175 _LGLGEGAEEK(gl)SIPTLISR_
RCC1 Phosphorylation S11 -0.620 -0.233 _S(ph)PPADAIPK_

Background Information for RCC1:





Protein-protein Interactions for RCC1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KPNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP107 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP153 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP98 Cat. description Hein, Mann, Cell 2015
Category members IP bait RANBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RANBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RCC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2I Cat. description Hein, Mann, Cell 2015
Category members IP bait RAN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBE2I Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RCC1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RCC1/BLIP-II IPR009091 0.24
Category members Reg_chr_condens IPR000408 0.23


Protein complexes (CORUM database) featuring RCC1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RCC1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members Pathway Pathway_196 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS 0 9.67
Category members Pathway Pathway_376 REACTOME_HIV_LIFE_CYCLE 0 9.45
Category members Pathway Pathway_374 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 0 7.57
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0031965 nuclear membrane Database 2.59
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0000794 condensed nuclear chromosome Database 1.58
Category members GO Category GO:0000082 G1/S transition of mitotic cell cycle Database 1.23
Category members Pathway Pathway_65 PID_MYC_ACTIV_PATHWAY 0 1.08
Category members GO Category GO:0042393 histone binding Database 0.94
Category members GO Category GO:0000790 nuclear chromatin Database 0.46
Category members GO Category GO:0007052 mitotic spindle organization Database 0.41
Category members Pathway Pathway_1255 BIOCARTA_RANMS_PATHWAY 0 0.35
Category members GO Category GO:0051225 spindle assembly Database 0.25
Category members GO Category GO:0007059 chromosome segregation Database 0.13
Category members GO Category GO:0007088 regulation of mitosis Database 0.07
Category members GO Category GO:0031492 nucleosomal DNA binding Database 0.01
Category members GO Category GO:0005087 Ran guanyl-nucleotide exchange factor activity Database 0


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