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Query: RABGEF1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RABGEF1 0 1.107 0.010 0.630

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RABGEF1 Ubiquitylation K263 -0.601 0.398 _LQREEEEAFASSQSSQGAQSLTFSK(gl)FEEK_
RABGEF1 Ubiquitylation K281 0.077 0.349 _K(gl)FFSASSR_
RABGEF1 Ubiquitylation K293 -0.236 0.148 _VGSKK(gl)EIQEAK_
RABGEF1 Ubiquitylation K457 -0.737 _DLAIQK(gl)R_
RABGEF1 Ubiquitylation K299 -1.563 -0.828 _EIQEAK(gl)APSPSINR_
RABGEF1 Ubiquitylation K292 -1.150 _VGSK(gl)KEIQEAK_
RABGEF1 Ubiquitylation K329 -0.156 _TFHK(gl)TGQEIYK_
RABGEF1 Ubiquitylation K336 0.080 _TGQEIYK(gl)QTK_

Background Information for RABGEF1:





Protein-protein Interactions for RABGEF1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CPNE2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CPNE5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EXOC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM189B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1984 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RABGEF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RABGEF1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_A20 IPR002653 0
Category members VPS9 IPR003123 0
Category members VPS9_subgr IPR013995 0


Protein complexes (CORUM database) featuring RABGEF1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RABGEF1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0005769 early endosome Database 1.26
Category members GO Category GO:0006897 endocytosis Database 0.31
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0055037 recycling endosome Database 0.29
Category members Pathway Pathway_685 PID_RAS_PATHWAY 0 0.14
Category members GO Category GO:0017112 Rab guanyl-nucleotide exchange factor activity Database 0


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