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Query: PVRL1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PVRL1 0 -0.043 0.150 0.290

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PVRL1 Phosphorylation S434 -0.333 _AGPLGGS(ph)SYEEEEEEEEGGGGGER_

Background Information for PVRL1:





Protein-protein Interactions for PVRL1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait LGALS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PVRL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PVRL1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ig-like_dom IPR007110 0.6
Category members Ig_sub IPR003599 0.43
Category members Immunoglobulin IPR013151 0.23
Category members Ig_sub2 IPR003598 0.21
Category members Ig_V-set IPR013106 0.09
Category members Ig_V-set_subgr IPR003596 0
Category members CD80_C2-set IPR013162 0


Protein complexes (CORUM database) featuring PVRL1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PVRL1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0006955 immune response Database 1.22
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005913 cell-cell adherens junction Database 1.05
Category members GO Category GO:0001618 virus receptor activity Database 0.83
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members Pathway Pathway_747 KEGG_ADHERENS_JUNCTION 0 0.43
Category members GO Category GO:0034329 cell junction assembly Database 0.29
Category members GO Category GO:0007156 homophilic cell adhesion Database 0.28
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members Pathway Pathway_560 REACTOME_CELL_CELL_COMMUNICATION 0 0.25
Category members GO Category GO:0005912 adherens junction Database 0.25
Category members GO Category GO:0030424 axon Database 0.23
Category members Pathway Pathway_581 PID_NECTIN_PATHWAY 0 0.21
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0045216 cell-cell junction organization Database 0.1
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members GO Category GO:0015026 coreceptor activity Database 0.07
Category members GO Category GO:0045202 synapse Database 0.06
Category members GO Category GO:0007157 heterophilic cell-cell adhesion Database 0.04
Category members GO Category GO:0046718 viral entry into host cell Database 0.04
Category members GO Category GO:0002089 lens morphogenesis in camera-type eye Database 0.01
Category members Pathway Pathway_1217 KEGG_CELL_ADHESION_MOLECULES_CAMS 0 0
Category members Pathway Pathway_1237 REACTOME_CELL_CELL_JUNCTION_ORGANIZATION 0 0
Category members Pathway Pathway_1276 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS 0 0
Category members Pathway Pathway_925 REACTOME_CELL_JUNCTION_ORGANIZATION 0 0
Category members Disease phenotype Cleft_Lip_+/-_Cleft_Palate Cleft Lip +/- Cleft Palate Database 0
Category members GO Category GO:0002934 desmosome organization Database 0
Category members GO Category GO:0004872 receptor activity Database 0
Category members GO Category GO:0006826 iron ion transport Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0016337 cell-cell adhesion Database 0
Category members GO Category GO:0030246 carbohydrate binding Database 0
Category members GO Category GO:0032584 growth cone membrane Database 0
Category members GO Category GO:0034332 adherens junction organization Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0046790 virion binding Database 0
Category members GO Category GO:0048593 camera-type eye morphogenesis Database 0
Category members GO Category GO:0050839 cell adhesion molecule binding Database 0
Category members GO Category GO:0051963 regulation of synapse assembly Database 0
Category members GO Category GO:0060041 retina development in camera-type eye Database 0
Category members GO Category GO:0070166 enamel mineralization Database 0


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