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Query: PTPN3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PTPN3 0 1.909 -0.300 0.200

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PTPN3 Phosphorylation S359 0.897 0.812 _SLS(ph)VEHLETK_

Background Information for PTPN3:


Pubmed-PTPN3 »
Uniprot-PTPN3 »
Biogrid-PTPN3 »
ProteomicsDB-PTPN3 »

Tumorportal-PTPN3 »
COSMIC-PTPN3 »
GenomeRNAi-PTPN3 »
Genecards-PTPN3


Protein-protein Interactions for PTPN3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait IGFBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PTPN3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members Ez/rad/moesin_like IPR000798 0.38
Category members FERM_N IPR018979 0.36
Category members FERM_PH-like_C IPR018980 0.35
Category members Band_41_fam IPR019750 0.33
Category members Tyr_Pase_non-rcpt_typ-3/4 IPR012151 0.17
Category members PDZ IPR001478 0.15
Category members Tyr_Pase_rcpt/non-rcpt IPR000242 0
Category members FERM_domain IPR000299 0
Category members Dual-sp_phosphatase_cat-dom IPR000340 0
Category members Tyr/Dual-sp_Pase IPR000387 0
Category members Tyr_Pase_cat IPR003595 0
Category members FERM_central IPR019748 0
Category members Band_41_domain IPR019749 0
Category members Prot-tyrosine_phosphatase-like IPR029021 0


Protein complexes (CORUM database) featuring PTPN3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PTPN3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0008092 cytoskeletal protein binding Database 0.5
Category members GO Category GO:0051045 negative regulation of membrane protein ectodomain proteolysis Database 0.04
Category members GO Category GO:0045930 negative regulation of mitotic cell cycle Database 0.01
Category members GO Category GO:0001784 phosphotyrosine binding Database 0
Category members GO Category GO:0004725 protein tyrosine phosphatase activity Database 0
Category members GO Category GO:0006470 protein dephosphorylation Database 0
Category members GO Category GO:0008138 protein tyrosine/serine/threonine phosphatase activity Database 0
Category members GO Category GO:0009898 cytoplasmic side of plasma membrane Database 0
Category members GO Category GO:0016311 dephosphorylation Database 0
Category members GO Category GO:0016791 phosphatase activity Database 0
Category members GO Category GO:0035335 peptidyl-tyrosine dephosphorylation Database 0
Category members GO Category GO:0051117 ATPase binding Database 0


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