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Query: PTP4A1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PTP4A1 0 2.729 0.520 -0.890
PTP4A1 0 2.729 0.520 -0.890 0.543 0.024

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PTP4A1 Ubiquitylation K141 1.064 1.099 _GAFNSK(gl)QLLYLEK_
PTP4A1 Ubiquitylation K15 -0.505 _MNRPAPVEVTYK(gl)NMR_

Background Information for PTP4A1:


Pubmed-PTP4A1 »
Uniprot-PTP4A1 »
Biogrid-PTP4A1 »
ProteomicsDB-PTP4A1 »

Tumorportal-PTP4A1 »
COSMIC-PTP4A1 »
GenomeRNAi-PTP4A1 »
Genecards-PTP4A1


Protein-protein Interactions for PTP4A1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CEP55 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF21B Cat. description Hein, Mann, Cell 2015
Category members IP bait AUP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FNTB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC39 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MBLAC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTP4A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RABGGTB Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PTP4A1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Tyr_Pase_rcpt/non-rcpt IPR000242 0
Category members Dual-sp_phosphatase_cat-dom IPR000340 0
Category members Tyr/Dual-sp_Pase IPR000387 0
Category members Tyr_Pase_cat IPR003595 0
Category members Prot-tyrosine_phosphatase-like IPR029021 0


Protein complexes (CORUM database) featuring PTP4A1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PTP4A1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005769 early endosome Database 1.26
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0005819 spindle Database 0.41
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members Pathway Pathway_1135 PID_PRL_SIGNALING_EVENTS_PATHWAY 0 0.27
Category members GO Category GO:0004725 protein tyrosine phosphatase activity Database 0
Category members GO Category GO:0006470 protein dephosphorylation Database 0
Category members GO Category GO:0008138 protein tyrosine/serine/threonine phosphatase activity Database 0
Category members GO Category GO:0009898 cytoplasmic side of plasma membrane Database 0
Category members GO Category GO:0016311 dephosphorylation Database 0
Category members GO Category GO:0016791 phosphatase activity Database 0
Category members GO Category GO:0030335 positive regulation of cell migration Database 0
Category members GO Category GO:0035335 peptidyl-tyrosine dephosphorylation Database 0


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