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Query: PSME3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PSME3 0 1.548 0.190 0.530 -0.215 -0.401

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PSME3 Ubiquitylation K132 0.536 0.916 _LLIEK(gl)CNTVK_
PSME3 Ubiquitylation K14 0.149 0.475 _LK(gl)VDSFRER_
PSME3 Phosphorylation T23 0.446 _IT(ph)SEAEDLVANFFPK_
PSME3 Phosphorylation S24 -0.264 0.279 _ITS(ph)EAEDLVANFFPK_
PSME3 Ubiquitylation K6 -0.128 0.024 _(ac)ASLLK(gl)VDQEVK_
PSME3 Ubiquitylation K12 0.437 _VDQEVK(gl)LK_
PSME3 Ubiquitylation K37 -0.209 _ITSEAEDLVANFFPKK(gl)_

Background Information for PSME3:


Pubmed-PSME3 »
Uniprot-PSME3 »
Biogrid-PSME3 »
ProteomicsDB-PSME3 »

Tumorportal-PSME3 »
COSMIC-PSME3 »
GenomeRNAi-PSME3 »
Genecards-PSME3


Protein-protein Interactions for PSME3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C1orf63 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX7 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PSMB4 Cat. description Hein, Mann, Cell 2015
Category members IP bait PSMB5 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZNF526 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAMTA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC69 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HUS1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHDC8A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPS34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PML Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPM1E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSMB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSMB9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSME3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB40AL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RASL10B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SSH3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TP53TG5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPYL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZMAT5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PSME3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Proteasome_activ_pa28_N IPR003185 0
Category members Proteasome_activ_pa28_C IPR003186 0
Category members Proteasome_activ_pa28 IPR009077 0


Protein complexes (CORUM database) featuring PSME3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 194 PA28gamma-20S proteasome Database 0.13


Categories featuring PSME3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle Database 3.38
Category members GO Category GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle Database 3.35
Category members GO Category GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle Database 3.26
Category members GO Category GO:0000502 proteasome complex Database 3.17
Category members GO Category GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process Database 2.59
Category members GO Category GO:0002474 antigen processing and presentation of peptide antigen via MHC class I Database 2.5
Category members GO Category GO:0000209 protein polyubiquitination Database 2.46
Category members GO Category GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent Database 2.46
Category members GO Category GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I Database 2.21
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0002039 p53 binding Database 2.06
Category members GO Category GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest Database 1.39
Category members Pathway Pathway_900 KEGG_PROTEASOME 0 1.34
Category members GO Category GO:0000082 G1/S transition of mitotic cell cycle Database 1.23
Category members GO Category GO:0042981 regulation of apoptotic process Database 0.79
Category members GO Category GO:0006521 regulation of cellular amino acid metabolic process Database 0.62
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_767 KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION 0 0.09
Category members GO Category GO:0010950 positive regulation of endopeptidase activity Database 0.04
Category members GO Category GO:0034641 cellular nitrogen compound metabolic process Database 0.01
Category members GO Category GO:0008537 proteasome activator complex Database 0
Category members GO Category GO:0061133 endopeptidase activator activity Database 0
Category members GO Category GO:0061136 regulation of proteasomal protein catabolic process Database 0


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