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Query: PRDX4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PRDX4 1 0.933 2.180 -0.730 -0.124 0.235 0.449 0.389 0.252

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PRDX4 Ubiquitylation K265 -0.267 0.111 _LK(gl)YFDKLN_

Background Information for PRDX4:


Pubmed-PRDX4 »
Uniprot-PRDX4 »
Biogrid-PRDX4 »
ProteomicsDB-PRDX4 »

Tumorportal-PRDX4 »
COSMIC-PRDX4 »
GenomeRNAi-PRDX4 »
Genecards-PRDX4


Protein-protein Interactions for PRDX4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BACH1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDCA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA3C;TUBA3E Cat. description Hein, Mann, Cell 2015


Protein Domains in PRDX4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Peroxiredoxin_C IPR019479 1.06
Category members Redoxin IPR013740 0.19
Category members Thioredoxin-like_fold IPR012336 0.16
Category members AhpC/TSA IPR000866 0.13


Protein complexes (CORUM database) featuring PRDX4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PRDX4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0051920 peroxiredoxin activity Database 0.94
Category members GO Category GO:0008379 thioredoxin peroxidase activity Database 0.35
Category members GO Category GO:0016209 antioxidant activity Database 0.06
Category members GO Category GO:0007252 I-kappaB phosphorylation Database 0
Category members GO Category GO:0007283 spermatogenesis Database 0
Category members GO Category GO:0008584 male gonad development Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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