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Query: PPIL2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PPIL2 1 1.468 -1.310 2.810 -0.614 -0.728

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for PPIL2:


Pubmed-PPIL2 »
Uniprot-PPIL2 »
Biogrid-PPIL2 »
ProteomicsDB-PPIL2 »

Tumorportal-PPIL2 »
COSMIC-PPIL2 »
GenomeRNAi-PPIL2 »
Genecards-PPIL2


Protein-protein Interactions for PPIL2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAIAP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC12 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait NAA15 Cat. description Hein, Mann, Cell 2015
Category members IP bait PDGFRA Cat. description Hein, Mann, Cell 2015
Category members IP bait PIM2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPIL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RACGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMAD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS26B Cat. description Hein, Mann, Cell 2015
Category members IP bait FGL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FKBP6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAPK14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NAGK Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PPIL2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Cyclophilin-type_PPIase_dom IPR002130 0.54
Category members Cyclophilin-like_dom IPR029000 0.54
Category members Rtf2_RING-finger IPR027799 0.13
Category members Ubox_domain IPR003613 0


Protein complexes (CORUM database) featuring PPIL2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3


Categories featuring PPIL2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006457 protein folding Database 4.93
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0000209 protein polyubiquitination Database 2.46
Category members Pathway Pathway_888 KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 0 2.22
Category members GO Category GO:0003755 peptidyl-prolyl cis-trans isomerase activity Database 1.31
Category members GO Category GO:0005796 Golgi lumen Database 0.64
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0000151 ubiquitin ligase complex Database 0.24
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members Pathway Pathway_600 REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL 0 0.05
Category members GO Category GO:0050900 leukocyte migration Database 0.04
Category members Pathway Pathway_927 REACTOME_BASIGIN_INTERACTIONS 0 0
Category members GO Category GO:0034450 ubiquitin-ubiquitin ligase activity Database 0


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