bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: POLR1A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
POLR1A 1 4.181 -1.130 0.600 0.018 -0.640
POLR1A 1 4.181 -1.130 0.600 0.940 0.421 0.350

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
POLR1A Ubiquitylation K1184 2.297 _SYEK(gl)SELSLDR_
POLR1A Ubiquitylation K981 0.277 _EGLVDTAVK(gl)TSR_
POLR1A Ubiquitylation K664 0.225 _GLTDK(gl)VGR_
POLR1A Ubiquitylation K1101 0.179 _IQEAVK(gl)ALK_
POLR1A Phosphorylation S1429 -0.141 _EKQEEEVDYES(ph)EEEEEREGEENDDEDMQEER_
POLR1A Ubiquitylation K1716 -0.858 _GGTGLFELK(gl)QPLR_
POLR1A Ubiquitylation K252 -1.523 _DSEPLGIEEAQIGK(gl)R_
POLR1A Ubiquitylation K1704 0.337 _SPSACLVVGK(gl)VVR_

Background Information for POLR1A:


Pubmed-POLR1A »
Uniprot-POLR1A »
Biogrid-POLR1A »
ProteomicsDB-POLR1A »

Tumorportal-POLR1A »
COSMIC-POLR1A »
GenomeRNAi-POLR1A »
Genecards-POLR1A


Protein-protein Interactions for POLR1A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait L1TD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR2F Cat. description Hein, Mann, Cell 2015
Category members IP bait ASB7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM46A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LOC554223 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIH1D1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLR1C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLR2E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SKAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TWISTNB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UXT Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in POLR1A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RNA_pol_asu IPR000722 0.68
Category members RNA_pol_N IPR006592 0.68
Category members RNA_pol_Rpb1_3 IPR007066 0.68
Category members RNA_pol_Rpb1_1 IPR007080 0.68
Category members RNA_pol_Rpb1_5 IPR007081 0.68
Category members RNA_pol_Rpb1_4 IPR007083 0.68


Protein complexes (CORUM database) featuring POLR1A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5233 TNF-alpha/NF-kappa B signaling complex 5 Database 0.29


Categories featuring POLR1A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_351 REACTOME_RNA_POL_I_TRANSCRIPTION 0 8.31
Category members Pathway Pathway_350 REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION 0 7.97
Category members Pathway Pathway_346 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION 0 3.42
Category members GO Category GO:0006360 transcription from RNA polymerase I promoter Database 2.66
Category members GO Category GO:0006361 transcription initiation from RNA polymerase I promoter Database 2.41
Category members Pathway Pathway_345 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION 0 1.9
Category members GO Category GO:0006363 termination of RNA polymerase I transcription Database 1.71
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006362 transcription elongation from RNA polymerase I promoter Database 1.47
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0001054 RNA polymerase I activity Database 1.02
Category members Pathway Pathway_349 KEGG_RNA_POLYMERASE 0 0.91
Category members GO Category GO:0005736 DNA-directed RNA polymerase I complex Database 0.78
Category members GO Category GO:0003899 DNA-directed RNA polymerase activity Database 0.46
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members Pathway Pathway_68 KEGG_PURINE_METABOLISM 0 0.23
Category members Pathway Pathway_277 KEGG_PYRIMIDINE_METABOLISM 0 0.18
Category members Pathway Pathway_347 BIOCARTA_ARF_PATHWAY 0 0.12


.

© Copyright Svejstrup Laboratory 2015