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Query: PLCD3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PLCD3 0 0.688 0.810 -0.250

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PLCD3 Phosphorylation S496 0.167 0.537 _ALS(ph)DREEEEEDDEEEEEEVEAAAQR_
PLCD3 Ubiquitylation K205 0.167 -0.183 _MSFK(gl)EIK_

Background Information for PLCD3:


Pubmed-PLCD3 »
Uniprot-PLCD3 »
Biogrid-PLCD3 »
ProteomicsDB-PLCD3 »

Tumorportal-PLCD3 »
COSMIC-PLCD3 »
GenomeRNAi-PLCD3 »
Genecards-PLCD3


Protein-protein Interactions for PLCD3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait AHCYL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARHGAP22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARIH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CASQ2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EAF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EFNB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPBP1L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR156 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRICKLE3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PLCD3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PH_domain IPR001849 0.14
Category members PI-PLC_fam IPR001192 0.03
Category members PLipase_C_Pinositol-sp_Y IPR001711 0.03
Category members PLipase_C_EF-hand-like IPR015359 0.03
Category members C2_dom IPR000008 0
Category members PLipase_C_PInositol-sp_X_dom IPR000909 0
Category members PLC-like_Pdiesterase_TIM-brl IPR017946 0


Protein complexes (CORUM database) featuring PLCD3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PLCD3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0032154 cleavage furrow Database 2.01
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_106 KEGG_INOSITOL_PHOSPHATE_METABOLISM 0 0.28
Category members Pathway Pathway_233 KEGG_CALCIUM_SIGNALING_PATHWAY 0 0.13
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0042127 regulation of cell proliferation Database 0.06
Category members Pathway Pathway_488 KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM 0 0
Category members GO Category GO:0001525 angiogenesis Database 0
Category members GO Category GO:0004435 phosphatidylinositol phospholipase C activity Database 0
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0006629 lipid metabolic process Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0008081 phosphoric diester hydrolase activity Database 0
Category members GO Category GO:0016042 lipid catabolic process Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0043647 inositol phosphate metabolic process Database 0
Category members GO Category GO:0060716 labyrinthine layer blood vessel development Database 0


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