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Query: PKN1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PKN1 0 2.756 -1.000 1.540 -0.016

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PKN1 Phosphorylation S562 0.231 1.001 _LNLGTDSDSS(ph)PQK_
PKN1 Phosphorylation S561 -0.165 0.098 _LNLGTDSDS(ph)SPQK_
PKN1 Phosphorylation S916 -0.482 -0.510 _TDVSNFDEEFTGEAPTLS(ph)PPR_
PKN1 Phosphorylation T914 -0.855 _TDVSNFDEEFTGEAPT(ph)LSPPRDAR_

Background Information for PKN1:


Pubmed-PKN1 »
Uniprot-PKN1 »
Biogrid-PKN1 »
ProteomicsDB-PKN1 »

Tumorportal-PKN1 »
COSMIC-PKN1 »
GenomeRNAi-PKN1 »
Genecards-PKN1


Protein-protein Interactions for PKN1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AEN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C10orf125 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1orf186 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COG6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAGEA10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLAUR Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PKN1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members HR1_rho-bd IPR011072 0.07
Category members Kinase-like_dom IPR011009 0.03
Category members C2_dom IPR000008 0
Category members Prot_kinase_dom IPR000719 0
Category members AGC-kinase_C IPR000961 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Pkinase_C IPR017892 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring PKN1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PKN1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0032154 cleavage furrow Database 2.01
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0042393 histone binding Database 0.94
Category members Pathway Pathway_308 PID_AR_TF_PATHWAY 0 0.86
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members Pathway Pathway_677 BIOCARTA_MYOSIN_PATHWAY 0 0.53
Category members GO Category GO:0030496 midbody Database 0.39
Category members GO Category GO:0005768 endosome Database 0.29
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members Pathway Pathway_428 PID_THROMBIN_PAR1_PATHWAY 0 0.18
Category members GO Category GO:0035402 histone kinase activity (H3-T11 specific) Database 0.18
Category members GO Category GO:0016023 cytoplasmic membrane-bounded vesicle Database 0.17
Category members GO Category GO:0042826 histone deacetylase binding Database 0.16
Category members GO Category GO:0010631 epithelial cell migration Database 0.15
Category members GO Category GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity Database 0.12
Category members GO Category GO:0050681 androgen receptor binding Database 0.12
Category members GO Category GO:0048365 Rac GTPase binding Database 0.1
Category members GO Category GO:0004697 protein kinase C activity Database 0.09
Category members GO Category GO:0007257 activation of JUN kinase activity Database 0.08
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0005080 protein kinase C binding Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_1129 PID_P38_GAMMA_DELTA_PATHWAY 0 0
Category members Pathway Pathway_1153 BIOCARTA_AKAPCENTROSOME_PATHWAY 0 0
Category members Pathway Pathway_668 PID_RHOA_PATHWAY 0 0
Category members GO Category GO:0006972 hyperosmotic response Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0017049 GTP-Rho binding Database 0


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