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Query: PIGU

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PIGU 0 1.545 -0.210 0.490 0.332 0.173

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PIGU Ubiquitylation K42 0.550 _VEVVSPLSSWK(gl)R_

Background Information for PIGU:


Pubmed-PIGU »
Uniprot-PIGU »
Biogrid-PIGU »
ProteomicsDB-PIGU »

Tumorportal-PIGU »
COSMIC-PIGU »
GenomeRNAi-PIGU »
Genecards-PIGU


Protein-protein Interactions for PIGU
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PIGS Cat. description Hein, Mann, Cell 2015
Category members IP bait CDH13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLEC5A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIGK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIGT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PVRL4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC6A15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPPL2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VNN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YIPF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PIGU
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring PIGU
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 994 GAA1-GPI8-PIGT-PIG-PIGS complex Database 0.13


Categories featuring PIGU
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016255 attachment of GPI anchor to protein Database 0.38
Category members GO Category GO:0003923 GPI-anchor transamidase activity Database 0.13
Category members GO Category GO:0042765 GPI-anchor transamidase complex Database 0.13
Category members GO Category GO:0006501 C-terminal protein lipidation Database 0.1
Category members GO Category GO:0046425 regulation of JAK-STAT cascade Database 0.08
Category members Pathway Pathway_461 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS 0 0.04
Category members Pathway Pathway_462 KEGG_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI_ANCHOR_BIOSYNTHESIS 0 0.04
Category members Pathway Pathway_94 REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 0 0
Category members GO Category GO:0006506 GPI anchor biosynthetic process Database 0
Category members GO Category GO:0030176 integral to endoplasmic reticulum membrane Database 0
Category members GO Category GO:0034235 GPI anchor binding Database 0
Category members GO Category GO:0043687 post-translational protein modification Database 0


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