Results for the Category
regulation of JAK-STAT cascade
(GO:0046425)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| DOT1L | 1 | -0.340 | 0.210 | -0.710 | -0.145 | |||
| PIGU | 0 | -0.210 | 0.490 | 0.332 | 0.173 | |||
| ELP2 | 0 | 0.130 | -0.470 | 0.142 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| DOT1L | Phosphorylation | S374 | -0.107 | -0.003 | _VAGPADAPMDS(ph)GAEEEK_ |
| DOT1L | Phosphorylation | S448 | 0.637 | 0.950 | _KNQTALDALHAQTVSQTAASS(ph)PQDAYR_ |
| DOT1L | Phosphorylation | T772 | 0.095 | _LSGLAAPDYT(ph)RLSPAK_ | |
| DOT1L | Phosphorylation | S775 | 0.015 | -0.688 | _LSGLAAPDYTRLS(ph)PAK_ |
| DOT1L | Phosphorylation | S834 | -1.490 | -1.900 | _PLS(ph)PGALQLAGEK_ |
| DOT1L | Phosphorylation | S1035 | -0.512 | -0.045 | _GDLPSDSGFS(ph)DPESEAK_ |
| DOT1L | Phosphorylation | S1104 | 0.384 | -0.103 | _RASAGTPSLSAGVS(ph)PK_ |
| DOT1L | Phosphorylation | S1213 | 0.118 | -0.125 | _IATISLESKS(ph)PPK_ |
| DOT1L | Phosphorylation | S1246 | 1.598 | 1.113 | _STFS(ph)PISDIGLAK_ |
| ELP2 | Ubiquitylation | K484 | -0.739 | _LFAPWK(gl)R_ | |
| ELP2 | Ubiquitylation | K524 | 0.072 | -0.086 | _FQFVSGADEK(gl)VLR_ |
| PIGU | Ubiquitylation | K42 | 0.550 | _VEVVSPLSSWK(gl)R_ |
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