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Query: PI4KB

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PI4KB 2 7.880 -1.640 3.640 2.483

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PI4KB Phosphorylation S511 1.008 0.749 _RLS(ph)EQLAHTPTAFK_
PI4KB Phosphorylation S428 0.388 0.410 _S(ph)VENLPECGITHEQR_
PI4KB Phosphorylation S268 -1.249 _RELPSLSPAPDTGLS(ph)PSK_
PI4KB Phosphorylation S266 -1.800 -1.618 _ELPSLSPAPDTGLS(ph)PSK_

Background Information for PI4KB:


Pubmed-PI4KB »
Uniprot-PI4KB »
Biogrid-PI4KB »
ProteomicsDB-PI4KB »

Tumorportal-PI4KB »
COSMIC-PI4KB »
GenomeRNAi-PI4KB »
Genecards-PI4KB


Protein-protein Interactions for PI4KB
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PI4KB Cat. description Hein, Mann, Cell 2015
Category members IP bait CASP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DNAJC10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KBTBD7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RDM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PI4KB
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PI3/4_kinase_cat_dom IPR000403 1.52
Category members Kinase-like_dom IPR011009 0.03


Protein complexes (CORUM database) featuring PI4KB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PI4KB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0048015 phosphatidylinositol-mediated signaling Database 0.98
Category members GO Category GO:0004430 1-phosphatidylinositol 4-kinase activity Database 0.68
Category members Pathway Pathway_501 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE 0 0.46
Category members GO Category GO:0005741 mitochondrial outer membrane Database 0.46
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005768 endosome Database 0.29
Category members Pathway Pathway_106 KEGG_INOSITOL_PHOSPHATE_METABOLISM 0 0.28
Category members GO Category GO:0006661 phosphatidylinositol biosynthetic process Database 0.06
Category members Pathway Pathway_103 REACTOME_PI_METABOLISM 0 0.04
Category members Pathway Pathway_521 PID_AVB3_INTEGRIN_PATHWAY 0 0.03
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_488 KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM 0 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0006644 phospholipid metabolic process Database 0
Category members GO Category GO:0006898 receptor-mediated endocytosis Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0016773 phosphotransferase activity, alcohol group as acceptor Database 0
Category members GO Category GO:0030867 rough endoplasmic reticulum membrane Database 0


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