bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: PHKA2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PHKA2 0 1.785 -0.110 0.540

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PHKA2 Phosphorylation S1015 1.066 0.529 _RFS(ph)ADEQFFSVGQAASSSAHSSK_
PHKA2 Phosphorylation S729 0.325 _S(ph)LNLVDSPQPLLEK_
PHKA2 Ubiquitylation K286 -0.415 _NEIISK(gl)LQGR_
PHKA2 Ubiquitylation K705 0.064 _DILSVMAK(gl)AK_
PHKA2 Ubiquitylation K707 0.064 _DILSVMAK(gl)AK_

Background Information for PHKA2:


Pubmed-PHKA2 »
Uniprot-PHKA2 »
Biogrid-PHKA2 »
ProteomicsDB-PHKA2 »

Tumorportal-PHKA2 »
COSMIC-PHKA2 »
GenomeRNAi-PHKA2 »
Genecards-PHKA2


Protein-protein Interactions for PHKA2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAG6;BAT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM82A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait MTX2 Cat. description Hein, Mann, Cell 2015
Category members IP bait OXNAD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PHKG2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1R3B Cat. description Hein, Mann, Cell 2015
Category members IP bait DOK4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MPPED1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PHKG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCEANC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PHKA2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glyco_hydro_15 IPR011613 0.02
Category members 6-hairpin_glycosidase-like IPR008928 0


Protein complexes (CORUM database) featuring PHKA2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PHKA2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_35 REACTOME_GLUCOSE_METABOLISM 0 1.79
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_34 REACTOME_METABOLISM_OF_CARBOHYDRATES 0 0.31
Category members GO Category GO:0006006 glucose metabolic process Database 0.28
Category members Pathway Pathway_66 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS 0 0.22
Category members Pathway Pathway_44 KEGG_INSULIN_SIGNALING_PATHWAY 0 0.21
Category members GO Category GO:0005980 glycogen catabolic process Database 0.2
Category members Pathway Pathway_514 ST_GAQ_PATHWAY 0 0.17
Category members Pathway Pathway_233 KEGG_CALCIUM_SIGNALING_PATHWAY 0 0.13
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members Pathway Pathway_513 ST_ADRENERGIC 0 0.08
Category members GO Category GO:0004689 phosphorylase kinase activity Database 0.08
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members Pathway Pathway_658 ST_GA13_PATHWAY 0 0
Category members Disease phenotype Glycogen_storage_disease_due_to_liver_phosphorylase_kinase_deficiency Glycogen storage disease due to liver phosphorylase kinase deficiency Database 0
Category members GO Category GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds Database 0
Category members GO Category GO:0005964 phosphorylase kinase complex Database 0
Category members GO Category GO:0005976 polysaccharide metabolic process Database 0
Category members GO Category GO:0006091 generation of precursor metabolites and energy Database 0
Category members GO Category GO:0006464 cellular protein modification process Database 0


.

© Copyright Svejstrup Laboratory 2015