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Query: PGAM5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PGAM5 0 -0.512 -0.280 0.420 -1.333 0.162 -0.092

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PGAM5 Ubiquitylation K141 -0.419 0.750 _LASLGLK(gl)FNK_
PGAM5 Ubiquitylation K88 -0.544 0.311 _NVESGEEELASK(gl)LDHYK_

Background Information for PGAM5:





Protein-protein Interactions for PGAM5

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CD2AP Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH7B Cat. description Hein, Mann, Cell 2015
Category members IP bait OSGEP Cat. description Hein, Mann, Cell 2015
Category members IP bait RBM8A Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC1A Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TTLL12 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA1C Cat. description Hein, Mann, Cell 2015
Category members IP bait ZNF187 Cat. description Hein, Mann, Cell 2015


Protein Domains in PGAM5

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members His_Pase_superF_clade-1 IPR013078 0
Category members His_PPase_superfam IPR029033 0


Protein complexes (CORUM database) featuring PGAM5

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5805 PGAM5-KEAP1-NRF2 complex Database 0


Categories featuring PGAM5

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members GO Category GO:0005741 mitochondrial outer membrane Database 0.46
Category members GO Category GO:0043547 positive regulation of GTPase activity Database 0.21
Category members GO Category GO:0005096 GTPase activator activity Database 0.19
Category members GO Category GO:0004721 phosphoprotein phosphatase activity Database 0.11
Category members GO Category GO:0016311 dephosphorylation Database 0
Category members GO Category GO:0016791 phosphatase activity Database 0
Category members GO Category GO:0070266 necroptotic process Database 0


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