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Query: PDS5A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PDS5A 1 8.211 0.590 -0.570 0.453 0.412
PDS5A 1 8.211 0.590 -0.570 -0.833 0.206 0.212 0.449 0.249

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PDS5A Ubiquitylation K974 0.230 0.773 _QCLLK(gl)NISIR_
PDS5A Phosphorylation S1305 0.624 0.507 _RAAVGQES(ph)PGGLEAGNAK_
PDS5A Ubiquitylation K558 1.282 0.231 _AQDFVKK(gl)_
PDS5A Ubiquitylation K366 5.856 _DLTEYLK(gl)VR_

Background Information for PDS5A:


Pubmed-PDS5A »
Uniprot-PDS5A »
Biogrid-PDS5A »
ProteomicsDB-PDS5A »

Tumorportal-PDS5A »
COSMIC-PDS5A »
GenomeRNAi-PDS5A »
Genecards-PDS5A


Protein-protein Interactions for PDS5A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCNB2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDCA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB7A Cat. description Hein, Mann, Cell 2015
Category members IP bait RAD21 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC1A Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2K Cat. description Hein, Mann, Cell 2015
Category members IP bait WAPAL Cat. description Hein, Mann, Cell 2015
Category members IP bait ZBTB48 Cat. description Hein, Mann, Cell 2015
Category members IP bait APLNR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BCL2L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BSG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C19orf75 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD83 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GYPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LAMP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPAR4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NT5E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAD21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCN2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC15A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC30A4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VIPR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PDS5A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26


Protein complexes (CORUM database) featuring PDS5A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1856 CDCA5-PDS5A-RAD21-SMC1A-PDS5B-SMC3 complex Database 1.25
Category members Corum 5432 Sororin-cohesin complex Database 1.25


Categories featuring PDS5A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0005694 chromosome Database 3.87
Category members GO Category GO:0000785 chromatin Database 2.59
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0000775 chromosome, centromeric region Database 0.29
Category members GO Category GO:0008156 negative regulation of DNA replication Database 0.03


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